MPND_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MPND_MOUSE
• UniProt AC: Q3TV65
• Protein Name: MPN domain-containing protein
• Gene Name: Mpnd
• Organism: Mus musculus (Mouse).
• Sequence Length: 487
• Protein Description: Probable protease..
• Protein Sequence: MAAPESLSPGATAEEAPEEDEDDAEAEDPERGTGSGGRSGSLGGSGGGTAGPGMALGGALTRRAVTLRVLLKDELLEPGEGVLSIYYLGRKFTGDLQLDGRIVWQETGQVFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKAAWLRRHQLHMPVATADESPTSEGEEEELLLEEEEEDVLAGVSSEDKGHRPPGKGSLEPEATPPGKRMDKVPVPIRYCMLGSRDSARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDTDTAATVEEEIYQVLFLRGLSLVGWYHSHPHSPAVPSLQDIDAQMEYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDYGIPMDVEMAYVQDSFLTNDVLQEMVMLAEFYKGAPDLVKFQEAWSPEHTYLDKLKMSLASRTPKDQGMCHVLEQVCSVLKQGS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAAPESLSP ------CCCCCCCCC	31.55	-
6	Phosphorylation	--MAAPESLSPGATA --CCCCCCCCCCCCH	32.84	26643407
8	Phosphorylation	MAAPESLSPGATAEE CCCCCCCCCCCCHHH	30.48	26643407
12	Phosphorylation	ESLSPGATAEEAPEE CCCCCCCCHHHCCCC	40.28	26643407
39	Phosphorylation	GTGSGGRSGSLGGSG CCCCCCCCCCCCCCC	35.69	24759943
41	Phosphorylation	GSGGRSGSLGGSGGG CCCCCCCCCCCCCCC	25.70	26643407
45	Phosphorylation	RSGSLGGSGGGTAGP CCCCCCCCCCCCCCC	32.25	26643407
49	Phosphorylation	LGGSGGGTAGPGMAL CCCCCCCCCCCCCHH	31.54	26643407
113	Phosphorylation	ETGQVFNSPSAWATH EECCEECCHHHHHHH	14.57	26745281
115	Phosphorylation	GQVFNSPSAWATHCK CCEECCHHHHHHHHH	35.94	26643407
119	Phosphorylation	NSPSAWATHCKKLVN CCHHHHHHHHHHHCC	19.66	26745281
168	Phosphorylation	PVATADESPTSEGEE CEEECCCCCCCCCHH	33.74	22802335
170	Phosphorylation	ATADESPTSEGEEEE EECCCCCCCCCHHHH	49.00	29514104
171	Phosphorylation	TADESPTSEGEEEEL ECCCCCCCCCHHHHH	47.16	22802335
205	Phosphorylation	HRPPGKGSLEPEATP CCCCCCCCCCCCCCC	32.80	25338131
211	Phosphorylation	GSLEPEATPPGKRMD CCCCCCCCCCCCCCC	28.49	25159016
226	Phosphorylation	KVPVPIRYCMLGSRD CCCCCCEEEECCCCC	5.28	-
282	Phosphorylation	TRSEVVGYLGGRWDI CHHHHHEEECCEEEC	7.20	-
457	Ubiquitination	PEHTYLDKLKMSLAS CCCCHHHHHHHHHHC	47.62	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MPND_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MPND_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MPND_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MPND_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.