MPND_DROME - dbPTM
MPND_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MPND_DROME
UniProt AC Q9VKJ1
Protein Name MPN domain-containing protein CG4751
Gene Name CG4751
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 1412
Subcellular Localization
Protein Description Probable protease..
Protein Sequence MENGVEHGVDESGENQVLSSSDGEGDCDGDGEVEGEVLQPPPPPPLQITNDCVGEGVQAEEGERAPATTGAVDVTPDPGPPPTDGAAPVAILEDNMCDKDVDSDAGDEDNDDETKENYEGFNGTGRTVTLQTLMAANVLQPGLGLMTIEYLGQKFVGDLLADGKIKSHETETIFLTPSAWAMHCKRIINPDKKSGCGWASVKYKGKKLDAYKNTYLRKCALQKETPLDDCELDAERKTDTPEIVVKRTVFAHNTVSNRNVVHDANMLIESVPFTSVGKLQPFLITVNSSALLLADFHCHLTVREVCGYLGGTWDMNTHTLSITKTYPCRSTRFDRQRAGEVERDIQKMMIQDQLLLVGWYHSHPKFQAEPTLRDCDAQLDYQIKMRGASDLTYTPCVSLIISPYYDENPTLESVVKCIWIVPPNENRQSMEYGRPMLMQYSVLPDKEIPEEVRSEIQLCVDYYSQYRSEMVKFRNIYNNDVTYNEKLKNTLYPKFPSKQSDKALWNWICAVLDCEQEDDFIPPKTIKIIDNDDLEVKEEDKPVVLMDLSGDVKINPPKEEQFSEAMGGLEDSGRKAEEESNAQAEQKASELKVMSLQEQLCMPSGLNMNPVRMLSPLATPNPTSLPPVLPNLGAPVLPATPSQLLPPQVPAVTAPPAITPAVTTSALTSALNASPRDSPITIQSNSASPAKFEVPVRASPSPAKSDTSSHASTSRTRNSPAPSPGKFSVSDIARNSPSITPNKYEAAAAALVPPAAACLPTANDLMAASLAQLAGQLPPNFLQGDLAALFQQQRKDYGSSSLNQLAAAAAKVGGSKQSNASASSGLNDPNVAAAVAAYSNSFNMPLPTGVGIGGSGNSNAHSSSKSKSERSSKSSSSSSSSNSSSTSNSYKTKLMKELDELKNDPLKMSELIRSPEYAALLLQQAEALGATTLGTLGFGSDYSYLTGAGLGVPAANALTGGQSSNSSSSKSSKSSPAAAAAAALSADYNNLIQASKLLGYDSYMQQSKQSNDLNAFLQQQMAVAAASIPPPPQTASSGSSNSSSSKKQQQLQQQQHQQQQQQQQQQAAAQADYTALLQTYTKLFDPNNQFAAAMSSNKHMAGAHNELSALLSSGVGVGGGASGGGSKQKQKDIQSDMLNQLLQLEKQDSEIKALLYRQNKAAADLDALFATPSGAVVGAGSSANAMKSGSSAGNSGVSGMSSPSSLSNQAAYYNALAQEKMQDYAAFFQQQHGKYGIPDPLSKTTLAANNMFMTPSALFKIQQESLSAMMMKPPKSTTPSSARTRESSASPALERLTPTKSASSGGSGGGGSNSNSGGKYNFSAVDLAISSVPSNTPSPAPSDGSSGSSHRRPSPDIGRLYGELAPPGALLGSGGVPKKRMEFASVADLAAPPPAKMPKNNMGDDILNLSHD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
103PhosphorylationMCDKDVDSDAGDEDN
CCCCCCCCCCCCCCC		29.2519429919
238PhosphorylationELDAERKTDTPEIVV
CCCHHCCCCCCCEEE		51.8627794539
240PhosphorylationDAERKTDTPEIVVKR
CHHCCCCCCCEEEEE		28.2219429919
549PhosphorylationPVVLMDLSGDVKINP
CEEEEECCCCCCCCC		28.7822817900
684PhosphorylationDSPITIQSNSASPAK
CCCEEEECCCCCCCE		28.9722817900
686PhosphorylationPITIQSNSASPAKFE
CEEEECCCCCCCEEE		35.0619429919
688PhosphorylationTIQSNSASPAKFEVP
EEECCCCCCCEEEEC		25.8019429919
699PhosphorylationFEVPVRASPSPAKSD
EEECEECCCCCCCCC		18.4919429919
701PhosphorylationVPVRASPSPAKSDTS
ECEECCCCCCCCCCC		34.6919429919
705PhosphorylationASPSPAKSDTSSHAS
CCCCCCCCCCCCCCC		48.5022817900
716PhosphorylationSHASTSRTRNSPAPS
CCCCCCCCCCCCCCC		33.6919429919
719PhosphorylationSTSRTRNSPAPSPGK
CCCCCCCCCCCCCCC		21.1019429919
723PhosphorylationTRNSPAPSPGKFSVS
CCCCCCCCCCCCCHH		48.6819429919
726AcetylationSPAPSPGKFSVSDIA
CCCCCCCCCCHHHHH		37.5421791702
728PhosphorylationAPSPGKFSVSDIARN
CCCCCCCCHHHHHHC		24.9725749252
1272AcetylationSLSAMMMKPPKSTTP
HHHHHHCCCCCCCCC		40.0321791702
1284PhosphorylationTTPSSARTRESSASP
CCCCCCCCCCCCCCH		38.2125749252
1287PhosphorylationSSARTRESSASPALE
CCCCCCCCCCCHHHH		28.1025749252
1288PhosphorylationSARTRESSASPALER
CCCCCCCCCCHHHHH		28.1919429919
1290PhosphorylationRTRESSASPALERLT
CCCCCCCCHHHHHHC		16.8019429919
1297PhosphorylationSPALERLTPTKSASS
CHHHHHHCCCCCCCC		34.8225749252
1354PhosphorylationGSSHRRPSPDIGRLY
CCCCCCCCCCHHHHH		33.1319429919
1410PhosphorylationGDDILNLSHD-----
CCCCCCCCCC-----		25.2419429919
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MPND_DROME !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MPND_DROME !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MPND_DROME !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MPND_DROME

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-699; SER-701; SER-705;SER-719; SER-723; SER-728; SER-1288; SER-1290 AND THR-1297, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory