dbPTM

MPK11_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MPK11_ARATH
UniProt AC	Q9LMM5
Protein Name	Mitogen-activated protein kinase 11
Gene Name	MPK11
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	369
Subcellular Localization
Protein Description
Protein Sequence	MSIEKPFFGDDSNRGVSINGGRYVQYNVYGNLFEVSKKYVPPLRPIGRGASGIVCAAWNSETGEEVAIKKIGNAFGNIIDAKRTLREIKLLKHMDHDNVIAIIDIIRPPQPDNFNDVHIVYELMDTDLHHIIRSNQPLTDDHSRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKIGDFGLARTKSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGEIMTREPLFPGRDYVQQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSVNAVDLLQKMLVFDPNRRITVDEALCHPYLAPLHEYNEEPVCVRPFHFDFEQPSLTEENIKELIYRESVKFNP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	RPIGRGASGIVCAAW CCCCCCCCCEEEEEE	31.70	28011693
190	Phosphorylation	GDFGLARTKSETDFM CCCCCCCCCCCCCHH	33.06	23776212
192	Phosphorylation	FGLARTKSETDFMTE CCCCCCCCCCCHHHH	45.15	23776212
194	Phosphorylation	LARTKSETDFMTEYV CCCCCCCCCHHHHHH	41.44	23776212
198	Phosphorylation	KSETDFMTEYVVTRW CCCCCHHHHHHHHHC	24.94	23776212
200	Phosphorylation	ETDFMTEYVVTRWYR CCCHHHHHHHHHCCC	7.34	24601666
203	Phosphorylation	FMTEYVVTRWYRAPE HHHHHHHHHCCCCHH	12.87	24243849

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MPK11_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
198	T	Phosphorylation		-
Dually phosphorylated on Thr-198 and Tyr-200, which activates the enzyme.

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MPK11_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MPK11_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MPK11_ARATH

Related Literatures of Post-Translational Modification