MOGS_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MOGS_MOUSE
• UniProt AC: Q80UM7
• Protein Name: Mannosyl-oligosaccharide glucosidase
• Gene Name: Mogs
• Organism: Mus musculus (Mouse).
• Sequence Length: 834
• Subcellular Localization: Endoplasmic reticulum membrane; Single-pass type II membrane protein.
• Protein Description: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor..
• Protein Sequence: MARGERRRRAAAAEGARPLERARAAGRRDGRAGGARGSASGAALAVVVLALAFGLSGRWVLAWLRVRRALTLHPAPSALPPDSSSPAVAPELFWGTYRPHVYFGMKTRSPKPLLTGLMWAQQGATPGTPPKLRHTCEQGDGVGPYGWEFHDGRTFGRQHIHDGALRLTTEFVKRPGGQHGGDWSWRVTVEPQASGTPSFPLVSLFFYVVTDGQEVLLPEIGAKGQLKSISGHTSELGDFRLTLLPPTSPGDTVPKHGSYNVFWSSNPGLPQLTDMVKSRLNSWFQHRPPGASPDRYLGLPGSLKWEERGPSGQGQFLIQQVTLKAPFSVEFVFESGSAATGGNQASGRLVGSQLTQALESHAAAFKERFEKTFQLKEKGLSPEEQALGQVALSGLLGGIGYFYGQGLVLPDTSMEGSEQKMDPALFPPVPLFSGVPSRSFFPRGFLWDEGFHQLVVQRWDPHLTREALGHWLGLLNADGWIGREQILGDEARARVPPEFLVQRAAHANPPTLLLPVVHMLEGHDPDDLAFLRKAFPRLHAWFSWLHQSQAGPVPLSYRWRGRDLALPTLLNPKTLPSGLDDYPRASHPSTAERHLDLRCWVALGARVLSQLAEQLGETEAAAELGPLAASLEEPGSLDELHWAPELGVFADFGNHTKAVQLKSRPPQGLVRVVGRPPPRLQYVDALGYVSLFPLLLQLLDPSSPRLGPLLDVLADSRHLWSPFGLRSLSASSLFYKQRNTEHDPPYWRGAVWLNINYLALGALHHYGHVEGPHKVQAAKLYHELRANVVRNVRQQYQATGFLWEQYSDQDGRGMGCRPFQGWTSLVLLIMAEEY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	RAGGARGSASGAALA CCCCCCCCHHHHHHH	17.44	21454597
40	Phosphorylation	GGARGSASGAALAVV CCCCCCHHHHHHHHH	30.57	21454597
56	Phosphorylation	LALAFGLSGRWVLAW HHHHHCCCHHHHHHH	27.05	21454597
136	S-nitrosocysteine	PPKLRHTCEQGDGVG CCCCCCCCCCCCCCC	2.76	-
136	S-nitrosylation	PPKLRHTCEQGDGVG CCCCCCCCCCCCCCC	2.76	20925432
654	N-linked_Glycosylation	GVFADFGNHTKAVQL EEEEECCCCCCEEEC	39.38	-
716	Phosphorylation	LLDVLADSRHLWSPF HHHHHHCCCCCCCCC	18.91	-
729	Phosphorylation	PFGLRSLSASSLFYK CCCCCCCCHHHCHHC	27.61	25338131
735	Phosphorylation	LSASSLFYKQRNTEH CCHHHCHHCCCCCCC	16.11	25338131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MOGS_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MOGS_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MOGS_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MOGS_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.