MLO7_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MLO7_ARATH
• UniProt AC: O22752
• Protein Name: MLO-like protein 7
• Gene Name: MLO7
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 542
• Subcellular Localization: Cell membrane ; Multi-pass membrane protein . Endomembrane system . In synergids of unfertilized mature female gametophytes, present in a punctate pattern of endomembranes throughout the cytoplasm. Become polarly localized to the basal half of the sy
• Protein Description: May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity). Controls pollen tube reception in the female gametophyte synergids..
• Protein Sequence: MITRSRCRRSLLWFLVFHGGATATGAPSGGKELSQTPTWAVAVVCTFLILISHLLEKGLQRLANWLWKKHKNSLLEALEKIKAELMILGFISLLLTFGEPYILKICVPRKAALSMLPCLSEDTVLFQKLAPSSLSRHLLAAGDTSINCKQGSEPLITLKGLHQLHILLFFLAIFHIVYSLITMMLSRLKIRGWKKWEQETLSNDYEFSIDHSRLRLTHETSFVREHTSFWTTTPFFFYVGCFFRQFFVSVERTDYLTLRHGFISAHLAPGRKFNFQRYIKRSLEDDFKLVVGISPVLWASFVIFLLFNVNGWRTLFWASIPPLLIILAVGTKLQAIMATMALEIVETHAVVQGMPLVQGSDRYFWFDCPQLLLHLIHFALFQNAFQITHFFWIWYSFGLKSCFHKDFNLVVSKLFLCLGALILCSYITLPLYALVTQMGSHMKKAVFDEQMAKALKKWHKDIKLKKGKARKLPSKTLGVSESFSLSSSSSATTLHRSKTTGHSSNIIYYKQEDEEDEMSDLEAGAEDAIDRIQQQEMQFHNS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
217	Phosphorylation	DHSRLRLTHETSFVR CCCCEEECCCCHHHH	15.95	25561503
220	Phosphorylation	RLRLTHETSFVREHT CEEECCCCHHHHHHC	21.62	27643528
221	Phosphorylation	LRLTHETSFVREHTS EEECCCCHHHHHHCC	20.82	30407730
486	Phosphorylation	VSESFSLSSSSSATT CCCCEECCCCCCCCE	27.29	19880383
490	Phosphorylation	FSLSSSSSATTLHRS EECCCCCCCCEEECC	31.42	23111157

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MLO7_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MLO7_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MLO7_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CNG18_ARATH	CNGC18	physical	22737156
SUC3_ARATH	SUT2	physical	22737156
CAAT6_ARATH	CAT6	physical	22737156

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.