| UniProt ID | MLEC_MOUSE | |
|---|---|---|
| UniProt AC | Q6ZQI3 | |
| Protein Name | Malectin | |
| Gene Name | Mlec | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 291 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Single-pass type I membrane protein. |
|
| Protein Description | Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan. May play a role in the early steps of protein N-glycosylation (By similarity).. | |
| Protein Sequence | MLRPRGAEGTAVALLRLLLLLLLLGPKLRGPGLGVVGAAGAGLPESVIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSTPEDQILYQTERYNEETFGYEVPVKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVRGEVSTFTGKLYIEFVKGYYDNPKVCALYILAGTVDDVPKLQPHPGLEKKEEEEEEEEYDEGSNLKRQTNKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 161 | Phosphorylation | IFDRVGHSTAHDEII CCCCCCCCCCCCCEE | 22.74 | - | |
| 162 | Phosphorylation | FDRVGHSTAHDEIIP CCCCCCCCCCCCEEC | 23.49 | - | |
| 178 | Phosphorylation | SIRKGKLSVRGEVST EEECCCEEEECEEEE | 17.16 | 22942356 | |
| 185 | Phosphorylation | SVRGEVSTFTGKLYI EEECEEEECCEEEEE | 30.32 | 28464351 | |
| 205 | S-palmitoylation | YYDNPKVCALYILAG CCCCHHHEEEEEEEC | 2.42 | 28526873 | |
| 238 | Phosphorylation | EEEEEEEYDEGSNLK HHHHHHHCCCCCCHH | 23.68 | 28066266 | |
| 242 | Phosphorylation | EEEYDEGSNLKRQTN HHHCCCCCCHHHHCC | 36.62 | 28066266 | |
| 245 | Acetylation | YDEGSNLKRQTNKNR CCCCCCHHHHCCCCC | 46.87 | 66695657 | |
| 245 | Ubiquitination | YDEGSNLKRQTNKNR CCCCCCHHHHCCCCC | 46.87 | 22790023 | |
| 248 | Phosphorylation | GSNLKRQTNKNRVQS CCCHHHHCCCCCCCC | 52.79 | 28066266 | |
| 267 | N-linked_Glycosylation | PNPYASDNSSLMFPI CCCCCCCCCCCHHHH | 30.88 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MLEC_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MLEC_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MLEC_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MLEC_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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