MK67I_MOUSE - dbPTM
MK67I_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MK67I_MOUSE
UniProt AC Q91VE6
Protein Name MKI67 FHA domain-interacting nucleolar phosphoprotein
Gene Name Nifk
Organism Mus musculus (Mouse).
Sequence Length 317
Subcellular Localization Nucleus, nucleolus. Chromosome. Localizes to mitotic chromosomes in conjunction with MKI67..
Protein Description
Protein Sequence MAGLAGPAKPSLALNPQEDSQFEKALTQIQGRTKKPQQKKKEKLNRGVVYLGHLPSTLSESHIYNYCAQFGDISRFRLSRSKRTGNSKGYAFVEFESEDVAKIVAETMDNYLFGERLLSCKFMPRKKVHKDLFSQRNALFHRPSFPAVKRYNRKRGHLQMLKMEYRFKKKEKLLRKKLAAKGIDYSFPSLVLPKPKNIAVAHRDSEGNQVLPDQKEGLSGEPRRKEKMMKEDISNNIPKKRKRSRRKKSSVDSQGPTPVCTPTFLERRKSQVMEVGGDKDDEIILKLPVPPVKEDTQKTPTSASPGGKRPRKRKSKQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MAGLAGPAK
------CCCCCCCCC
23.00-
20PhosphorylationALNPQEDSQFEKALT
CCCCCCCHHHHHHHH
35.7026643407
50PhosphorylationKLNRGVVYLGHLPST
HHCCCEEEECCCCCC
12.4525293948
56PhosphorylationVYLGHLPSTLSESHI
EEECCCCCCCCHHHH
48.6325293948
57PhosphorylationYLGHLPSTLSESHIY
EECCCCCCCCHHHHH
32.1525293948
59PhosphorylationGHLPSTLSESHIYNY
CCCCCCCCHHHHHHH
36.8225293948
61PhosphorylationLPSTLSESHIYNYCA
CCCCCCHHHHHHHHH
16.2925293948
64PhosphorylationTLSESHIYNYCAQFG
CCCHHHHHHHHHHHC
8.4825293948
66PhosphorylationSESHIYNYCAQFGDI
CHHHHHHHHHHHCCE
3.3825293948
74PhosphorylationCAQFGDISRFRLSRS
HHHHCCEEEEEEECC
30.0625293948
116MethylationDNYLFGERLLSCKFM
HHHHHHHHHHCCCCC
41.11-
144PhosphorylationNALFHRPSFPAVKRY
CHHHCCCCCHHHHHH
43.7628725479
203CitrullinationKNIAVAHRDSEGNQV
CCEEEEEECCCCCEE
39.14-
203CitrullinationKNIAVAHRDSEGNQV
CCEEEEEECCCCCEE
39.1424463520
205PhosphorylationIAVAHRDSEGNQVLP
EEEEEECCCCCEECC
47.5725619855
219PhosphorylationPDQKEGLSGEPRRKE
CCCCCCCCCCCHHHH
52.55-
249PhosphorylationKRSRRKKSSVDSQGP
HHHHHHHCCCCCCCC
38.3325619855
250PhosphorylationRSRRKKSSVDSQGPT
HHHHHHCCCCCCCCC
38.5325619855
253PhosphorylationRKKSSVDSQGPTPVC
HHHCCCCCCCCCCCC
34.5822942356
257PhosphorylationSVDSQGPTPVCTPTF
CCCCCCCCCCCCHHH
34.8727149854
261PhosphorylationQGPTPVCTPTFLERR
CCCCCCCCHHHHHHH
26.1222942356
263PhosphorylationPTPVCTPTFLERRKS
CCCCCCHHHHHHHHH
23.7725619855
267MethylationCTPTFLERRKSQVME
CCHHHHHHHHHHHEE
54.17-
268MethylationTPTFLERRKSQVMEV
CHHHHHHHHHHHEEE
33.33-
270PhosphorylationTFLERRKSQVMEVGG
HHHHHHHHHHEEECC
26.6225521595
296PhosphorylationVPPVKEDTQKTPTSA
CCCCCCCCCCCCCCC
32.8128066266
299PhosphorylationVKEDTQKTPTSASPG
CCCCCCCCCCCCCCC
23.2125159016
301PhosphorylationEDTQKTPTSASPGGK
CCCCCCCCCCCCCCC
42.0025159016
302PhosphorylationDTQKTPTSASPGGKR
CCCCCCCCCCCCCCC
28.1425159016
304PhosphorylationQKTPTSASPGGKRPR
CCCCCCCCCCCCCCC
24.6827087446
308AcetylationTSASPGGKRPRKRKS
CCCCCCCCCCCCCCC
66.216569827

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MK67I_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MK67I_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MK67I_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MK67I_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MK67I_MOUSE

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Related Literatures of Post-Translational Modification

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