MITD1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MITD1_MOUSE
• UniProt AC: Q8VDV8
• Protein Name: MIT domain-containing protein 1
• Gene Name: Mitd1
• Organism: Mus musculus (Mouse).
• Sequence Length: 249
• Subcellular Localization: Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Midbody. Membrane; Peripheral membrane protein; Cytoplasmic side. During cytokinesis, recruited to the midbody via interaction with CHMP1A. Interacts with membranes enriched in ph
• Protein Description: Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex..
• Protein Sequence: MAKSSLGQDSDSTAAVAVLKRAVELDAESRYQQALVCYQEGIDMLLQVLKGTKESSKRCVLRTKISGYMDRAENIKKYLDQEKEDGKYHKQIKIEENATGFSYESLFREYLHETVTEVWIEDPYIRQTHQLYNFLRFCEMLIKKPCKVRTIHLLTSGYEGLGNTQQSSGLEEIKQSLGSHGVVLEINYSSSIHDREIRFNNGWMIKIGRGLDYFKKPQGRFSLGYYDLDLRPCHETTVDIFHNKHTKKI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Acetylation	-----MAKSSLGQDS -----CCCCCCCCCC	39.00	23806337
225	Phosphorylation	QGRFSLGYYDLDLRP CCCEECEEEECCCCC	10.09	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MITD1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MITD1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MITD1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MITD1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.