dbPTM

MIRO2_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MIRO2_RAT
UniProt AC	Q7TSA0
Protein Name	Mitochondrial Rho GTPase 2
Gene Name	Rhot2
Organism	Rattus norvegicus (Rat).
Sequence Length	622
Subcellular Localization	Mitochondrion outer membrane Single-pass type IV membrane protein. Colocalizes with MGARP and RHOT2 at the mitochondria..
Protein Description	Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity)..
Protein Sequence	MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTEEELQEEIHKANVVCVVYDVSEEATIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTIEAVLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRLSDQDLDHALSDKELNAFQKSCFGHPLAPQALEDVKRVVCKNVAGGVQDDRLTLEGFLFLNTLFIQRGRHETTWTILRRFGYSDSLELTPDYLCPPLYVPPGCSTELNHRGYQFVQRVFEKHDQDHDGVLSPTELESLFSVFSVAPWGPELLHTVPTEAGCLSLRGYLCQWTLVTYLDVQHCLAHLGYLGYPTLCEQDSQAQAITVTREKRLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGHSLGEARDRDAPEKLPTHTINTVRVSGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPETFVQCATIYKRYYMDGQTPCLFISSKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAQSSIDVFTQLATMATFPHLAHTELHPTPFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
453	Ubiquitination	RDRDAPEKLPTHTIN CCCCCCCCCCCCCEE	59.72	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MIRO2_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MIRO2_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MIRO2_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MIRO2_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MIRO2_RAT

Related Literatures of Post-Translational Modification