UniProt ID | MIRO2_MOUSE | |
---|---|---|
UniProt AC | Q8JZN7 | |
Protein Name | Mitochondrial Rho GTPase 2 | |
Gene Name | Rhot2 | |
Organism | Mus musculus (Mouse). | |
Sequence Length | 620 | |
Subcellular Localization |
Mitochondrion outer membrane Single-pass type IV membrane protein. Colocalizes with MGARP and RHOT2 at the mitochondria.. |
|
Protein Description | Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).. | |
Protein Sequence | MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTEEELQEEIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTMEAVLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRLSDQDRDHGLSDEELNAFQKSCFGHPLAPQALEDVKRVVCKNVSGGVQNDRLTLEGFLFLNTLFIQRGRHETTWTILRRFGYSDSLELTPDYLYPALHVPPGCSTELNHRGYQFVQRMFEKHDQDHDGVLSPTELQNLFSVFSGAPWGPELLHTVPTQAGCLPLHGYLCQWTLMTYLDVQQCLAHLGYLGYPTLCEQDSQAQAITVTREKKLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGNSLGEARDPPEKFPLHTINTVRVNGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPKTFVHCATIYKRYYMDGQTPCLFIASKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAMPSTDVFTQLATMATFPHLVHTELHPTSFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
59 | Phosphorylation | PTHIVDYSEAEQTEE CCCEECHHHHHHCHH | 26.35 | 30352176 | |
216 | S-palmitoylation | LNAFQKSCFGHPLAP HHHHHHHHHCCCCCH | 6.45 | 28526873 | |
235 | Malonylation | DVKRVVCKNVSGGVQ HHHHHEEECCCCCCC | 49.09 | 26320211 | |
261 | Methylation | LNTLFIQRGRHETTW EEEHHHHCCCCCCHH | 39.02 | 30989217 | |
421 | Ubiquitination | QRSVLMCKVLGARGV HHHHHHHHHHCCCCC | 26.91 | 22790023 | |
511 | Acetylation | VHCATIYKRYYMDGQ EEECEEEHHHCCCCC | 30.03 | 23201123 | |
511 | Malonylation | VHCATIYKRYYMDGQ EEECEEEHHHCCCCC | 30.03 | 26320211 | |
545 | S-nitrosocysteine | GLSPAEFCRRHRLPA CCCHHHHHHHCCCCC | 2.55 | - | |
545 | S-nitrosylation | GLSPAEFCRRHRLPA CCCHHHHHHHCCCCC | 2.55 | 21278135 | |
545 | S-palmitoylation | GLSPAEFCRRHRLPA CCCHHHHHHHCCCCC | 2.55 | 28680068 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MIRO2_MOUSE !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MIRO2_MOUSE !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MIRO2_MOUSE !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
Oops, there are no PPI records of MIRO2_MOUSE !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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