MIRO2_MOUSE - dbPTM
MIRO2_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MIRO2_MOUSE
UniProt AC Q8JZN7
Protein Name Mitochondrial Rho GTPase 2
Gene Name Rhot2
Organism Mus musculus (Mouse).
Sequence Length 620
Subcellular Localization Mitochondrion outer membrane
Single-pass type IV membrane protein. Colocalizes with MGARP and RHOT2 at the mitochondria..
Protein Description Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity)..
Protein Sequence MRRDVRILLLGEAQVGKTSLILSLVGEEFPEEVPARAEEITIPADVTPEKVPTHIVDYSEAEQTEEELQEEIHKANVVCVVYDVSEETTIEKIRTKWIPLVNGRTATGPRLPIILVGNKSDLRPGSTMEAVLPIMSQFPEIETCVECSAKHLRNISELFYYAQKAVLHPTAPLYDPEAKQLRPACAQALTRIFRLSDQDRDHGLSDEELNAFQKSCFGHPLAPQALEDVKRVVCKNVSGGVQNDRLTLEGFLFLNTLFIQRGRHETTWTILRRFGYSDSLELTPDYLYPALHVPPGCSTELNHRGYQFVQRMFEKHDQDHDGVLSPTELQNLFSVFSGAPWGPELLHTVPTQAGCLPLHGYLCQWTLMTYLDVQQCLAHLGYLGYPTLCEQDSQAQAITVTREKKLDQEKGQTQRSVLMCKVLGARGVGKSAFLQAFLGNSLGEARDPPEKFPLHTINTVRVNGQEKYLILCEVNADSLLDTSLDTTCDVACLMFDSSDPKTFVHCATIYKRYYMDGQTPCLFIASKADLPEGVAPPGLSPAEFCRRHRLPAPASFSCLGPAMPSTDVFTQLATMATFPHLVHTELHPTSFWLRGVLVAVGTAVAAVLSFSLYRVLVKSR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
59PhosphorylationPTHIVDYSEAEQTEE
CCCEECHHHHHHCHH
26.3530352176
216S-palmitoylationLNAFQKSCFGHPLAP
HHHHHHHHHCCCCCH
6.4528526873
235MalonylationDVKRVVCKNVSGGVQ
HHHHHEEECCCCCCC
49.0926320211
261MethylationLNTLFIQRGRHETTW
EEEHHHHCCCCCCHH
39.0230989217
421UbiquitinationQRSVLMCKVLGARGV
HHHHHHHHHHCCCCC
26.9122790023
511AcetylationVHCATIYKRYYMDGQ
EEECEEEHHHCCCCC
30.0323201123
511MalonylationVHCATIYKRYYMDGQ
EEECEEEHHHCCCCC
30.0326320211
545S-nitrosocysteineGLSPAEFCRRHRLPA
CCCHHHHHHHCCCCC
2.55-
545S-nitrosylationGLSPAEFCRRHRLPA
CCCHHHHHHHCCCCC
2.5521278135
545S-palmitoylationGLSPAEFCRRHRLPA
CCCHHHHHHHCCCCC
2.5528680068

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MIRO2_MOUSE !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MIRO2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MIRO2_MOUSE !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MIRO2_MOUSE !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MIRO2_MOUSE

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Related Literatures of Post-Translational Modification

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