dbPTM

MIP2_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MIP2_ARATH
UniProt AC	Q9FIN7
Protein Name	MAG2-interacting protein 2 {ECO:0000303\|PubMed:24118572}
Gene Name	MIP2 {ECO:0000303\|PubMed:24118572}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	2376
Subcellular Localization	Endoplasmic reticulum membrane Peripheral membrane protein .
Protein Description	Required for proper maturation of seed storage proteins. Forms a complex with MAG2, ZW10/MIP1 and MIP3 on the endoplasmic reticulum that may be responsible for efficient transport of seed storage proteins..
Protein Sequence	MESPGRKVLYEIRHHASLPYVPRYPPLPQADGTNSKGGLRSLVSIKGVSQLKEKWSEYWNPKKTNKPVSLFISPRGELVAVTSGNHVTILRKDDDYRKPCGNFTSSISGSFTSGVWSEKHDVLGLVDDSETLFFIRANGEEISQVTKRNLKVSAPVLGLMEDDSDLQPSCLCSFSILTSDGRIHHVEISREPSASAFSKHASNSVSKQFPNHVFCFDYHPDLSFLLIVGSVAGISSSGSSGSSCISLWRKCQNLGLELLSTTKFDGVYCENKDDQLAYPKTLISPQGSHVASLDSNGCVHIFQLDKARLTLSCCPSEDSSDSLKPDKSLQSWKESLRNVVDFTWWSDHALAILKRSGNISIFDISRCVIVQEDATIYSMPVVERVQKYEGHIFLLESSTQEAKSALANVDRDASEFHHTSEHSMLWRLISFTEKTIPEMYKILVEKCQYQEALDFSDSHGLDRDEVFKSRWLKSEKGVSDVSTILSKIKDKAFVLSECLDRIGPTEDSMKALLAHGLYLTNHYVFAKSEDQESQQLWEFRLARLRLLQFSERLDTYLGISMGRYSVQDYRKFRSNPINQAAISLAESGRIGALNLLFKRHPYSLVSFMLQILAAIPETVPVETYAHLLPGKSPPTSMAVREEDWVECEKMVKFINNLPENGKNDSLIQTEPIVRRCLGYNWPSSEELAAWYKSRARDIDSTTGLLDNCICLIDIACRKGISELEQFHEDLSYLHQIIYSDEIGGEICFSLSLAGWEHLSDYEKFKIMLEGVKADTVVRRLHEKAIPFMQKRFLGTNNQNVESFLVKWLKEMAAKSDMDLCSKVIDEGCIDLYTVCFFKDDVEAVDCALQCLYLCKVTDKWNVMATMLSKLPKINDKAGEDIQRRLKRAEGHIEAGRLLEFYQVPKPINYFLEVHLDEKGVKQILRLMLSKFVRRQPGRSDNDWACMWRDLRQLQEKAFYFLDLEFVLTEFCRGLLKAGKFSLARNYLKGTGSVALPSEKAESLVINAAKEYFFSAPSLASEEIWKARECLNIFSSSRTVKAEDDIIDAVTVRLPKLGVSLLPVQFKQVKDPMEIIKMAITGDPEAYLHGEELIEVAKLLGLNSSEDISSVKEAIAREAAIAGDMQLAFDLCLVLTKEGHGPIWDLGAAIARSPALEHMDISSRKQLLGFALGHCDDESISELLHAWKDFDLQGQCETLGMLSESNSPEFQKMDGVSCLTDFPQMLDGLSSDQQLDLDRAKDSISCVAKDMPVDDSVDLESLLKENGKLFSFAASHLPWLLKLGRNRKLDKSLVLDSIPGKQFVSIKATALITILSWLAKNGFAPKDELIAMITDSIIEHPVTKEEDVIGCSFLLNLVDASNAVEVIEKQLRIRGNYQEIRSIMSLGMIYSLLHDSGVECTAPIQRRELLQKNFERKQTESLADDMSKIDKLQSTFWKEWKHKLEEKMHDADRSRMLERIIPGVETERFLSHDIEYIKVAVFSLIESVKSEKKLILKDVLKLADTYGLKQSEVILRYLSSILCSEIWTNEDITAEILQVKEEILTFASDTIETISTIVYPAASGLNKQRLAYIYSLLSECYCHLAESKEASLLVQPNSSFAGLSNWYNVLKQECSRVSFIKDLDFKNISELGGLNFDSFNNEVHAHINEMNLEALAKMVETLSGLSMENSSKGLISCQDVYKQYIMNLLDTLESRRDLDFGSAESFQGFLGQLEKTYDHCRVYVRILEPLQAVEILKRHFTLVLPPNGSYMHIPDSSTWQECLILLINFWIRLADEMQEVKSSNPSLVENLTLSPECISSCFTLLIKLVMYDSLSPSQAWAAILVYLRSGLVGDCATEIFNFCRAMVFSGCGFGPISDVFSDMSSRYPTALQDLPHLYLSVLEPILQDLVSGAPETQNLYRLLSSLSNLEGNLEELKRVRLVVWKQLVIFSENLELPSQVRVYSLELMQFISGKNIKGSSSELQSNVMPWDGSAELLSSMQKTEAALNQALPDQADGSSRLTNTLVALKSSQVAVAAISPGLEISPEDLSTVETSVSCFSKLSAAVTTASQAEALLAILEGWEELFEAKNAELLPSNEATDQGNDWGDDDWNDGWETLQESEPVEKVKKECVVSAHPLHSCWLDIFRKYIALSMPENVLQLIDGSLQKPEEVIIEETEAESLTGILARTDPFLALKISLLLPYKQIRSQCLSVVEEQLKQEGIPELSSQSHHEVLLLVIYSGTLSTIISNACYGSVFSFLCYLIGKLSREFQEERITQADNRESNASSESRFISCFGQLMFPCFVSGLVKADQQILAGFLVTKFMHSNPSLSLINVAEASLRRYLDKQLESLEHLEDSFAESSDFETLKNTVSSLRGTSKEVIRSALASLSNCTNSR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
260	Phosphorylation	NLGLELLSTTKFDGV HHCCCHHHCCCCCCE	28295753
261	Phosphorylation	LGLELLSTTKFDGVY HCCCHHHCCCCCCEE	28295753
262	Phosphorylation	GLELLSTTKFDGVYC CCCHHHCCCCCCEEE	28295753
992	Phosphorylation	NYLKGTGSVALPSEK HHCCCCCCCCCCHHH	24894044
997	Phosphorylation	TGSVALPSEKAESLV CCCCCCCHHHHHHHH	24894044
1270	Phosphorylation	KENGKLFSFAASHLP HHCCEEHHHHHHHHH	19880383
1274	Phosphorylation	KLFSFAASHLPWLLK EEHHHHHHHHHHHHH	19880383
1504	Phosphorylation	DVLKLADTYGLKQSE HHHHHHHHHCCCHHH	28295753
1505	Phosphorylation	VLKLADTYGLKQSEV HHHHHHHHCCCHHHH	28295753

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MIP2_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MIP2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MIP2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MIP2_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MIP2_ARATH

Related Literatures of Post-Translational Modification