MINY4_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MINY4_MOUSE
• UniProt AC: Q3UQI9
• Protein Name: Probable ubiquitin carboxyl-terminal hydrolase MINDY-4
• Gene Name: Mindy4
• Organism: Mus musculus (Mouse).
• Sequence Length: 744
• Protein Description: Probable hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins..
• Protein Sequence: MDSLYVEEVAASLVREFLSRKGLNKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYKENKAKEKPLRTNLELITRYFLDNVGNTDNSESQEVPIPAIPVPKKNNKLPLRHSETTLVNIYDLSDEDTGRRTSWSEAGKARHDSLDGDILGNFVSSKKPSHKSKAAHVDLGDSLPLVPAWEKVDQLHSSEPGIDVKKTMERTRPKSGLIVRGMMAGPVASSPQDSFRKRSLRRSSALSRKLQTPEEIQQQSEPFVHTPAYLGPQEVPDSSSDSVSRSPLGQLNELSIEKPNVTSSSQGLSQRDRPRLRSVSEDSPLGYSHTEGNSRMAQDQLERAFKRQGVQPPSLRKNQLVSDRTDDKPDALQLEDVEDELIKEDIVLFPPPSMLKLQTVSKPIDLSLAKEIKTLLFGSTFCCFSEEWKLQNFSFNDIASLKYGIVQNKGGPCGVLAAVQGCVLQKLLFEGDNRTNSNLRLQPSDAQRTRCLALAIADILWRAGGKEQAVVALASGTPHFSPTGKYKADGVLETLTLYSLTSSEDLVTFIQQSVHQFEAGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNITLLRGIEARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLCDWRSERLFDLYYYDGLANQQEEIRLTVDTTKTAPADSCSDLVPPLELCIRTKWKGASVNWNGSDPIL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26	Phosphorylation	SRKGLNKTFVTMDQE HHCCCCCEEEECCCC		28059163
29	Phosphorylation	GLNKTFVTMDQERPR CCCCEEEECCCCCCC		28059163
112	Phosphorylation	NKLPLRHSETTLVNI CCCCCCCCCCEEEEE		25293948
114	Phosphorylation	LPLRHSETTLVNIYD CCCCCCCCEEEEEEE		25293948
115	Phosphorylation	PLRHSETTLVNIYDL CCCCCCCEEEEEEEC		25293948
120	Phosphorylation	ETTLVNIYDLSDEDT CCEEEEEEECCCCCC		23984901
123	Phosphorylation	LVNIYDLSDEDTGRR EEEEEECCCCCCCCC		26824392
127	Phosphorylation	YDLSDEDTGRRTSWS EECCCCCCCCCCCHH		23984901
131	Phosphorylation	DEDTGRRTSWSEAGK CCCCCCCCCHHHHHH		24899341
132	Phosphorylation	EDTGRRTSWSEAGKA CCCCCCCCHHHHHHH		23684622
134	Phosphorylation	TGRRTSWSEAGKARH CCCCCCHHHHHHHHH		26026062
143	Phosphorylation	AGKARHDSLDGDILG HHHHHHHCCCCCCHH		26824392
163	Methylation	KKPSHKSKAAHVDLG CCCCCCCCCCCCCCC		-
204	Acetylation	TMERTRPKSGLIVRG HHHHHCCCCCEEEEC		6566349
220	Phosphorylation	MAGPVASSPQDSFRK ECCCCCCCCCHHHHH		-
224	Phosphorylation	VASSPQDSFRKRSLR CCCCCCHHHHHHHHH		-
227	Ubiquitination	SPQDSFRKRSLRRSS CCCHHHHHHHHHHHH		-
234	Phosphorylation	KRSLRRSSALSRKLQ HHHHHHHHHHHHHCC		29899451
285	Phosphorylation	LGQLNELSIEKPNVT CHHHCCCEECCCCCC		29899451
295	Phosphorylation	KPNVTSSSQGLSQRD CCCCCCCCCCCCCCC		-
308	Phosphorylation	RDRPRLRSVSEDSPL CCCCCCCCCCCCCCC		30635358
310	Phosphorylation	RPRLRSVSEDSPLGY CCCCCCCCCCCCCCC		26160508
313	Phosphorylation	LRSVSEDSPLGYSHT CCCCCCCCCCCCCCC		26160508
317	Phosphorylation	SEDSPLGYSHTEGNS CCCCCCCCCCCCCCC		30635358
505	Phosphorylation	QAVVALASGTPHFSP HHEEEEECCCCCCCC		25293948
507	Phosphorylation	VVALASGTPHFSPTG EEEEECCCCCCCCCC		25293948
511	Phosphorylation	ASGTPHFSPTGKYKA ECCCCCCCCCCCCCC		25293948
513	Phosphorylation	GTPHFSPTGKYKADG CCCCCCCCCCCCCCC		25293948

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MINY4_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MINY4_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MINY4_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MINY4_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.