MICU3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MICU3_HUMAN
• UniProt AC: Q86XE3
• Protein Name: Calcium uptake protein 3, mitochondrial
• Gene Name: MICU3
• Organism: Homo sapiens (Human).
• Sequence Length: 530
• Subcellular Localization: Mitochondrion. Membrane ; Single-pass membrane protein .
• Protein Description: May play a role in mitochondrial calcium uptake..
• Protein Sequence: MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIPVAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLRLQLYGYHSPTNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
44	Phosphorylation	GLPGRPFSSREDEER CCCCCCCCCHHHHHH		24719451
68	Phosphorylation	RRRWGELSVAAAAGG HHHHCHHHHHHHHCC		24719451
83	Phosphorylation	GLVGLVCYQLYGDPR CHHEEEEHHHHCCCC		24719451
86	Phosphorylation	GLVCYQLYGDPRAGS EEEEHHHHCCCCCCC		24719451
100	Phosphorylation	SPATGRPSKSAATEP CCCCCCCCCCCCCCC		-
102	Phosphorylation	ATGRPSKSAATEPED CCCCCCCCCCCCCCC		-
184	Acetylation	PKVAKTWKSLSKQEL HHHHHHHHHCCHHHH		20167786
188	Acetylation	KTWKSLSKQELNQML HHHHHCCHHHHHHHH		20167786
334	Phosphorylation	AERADDITSLVTDTT HHHHHHHHHHHCCCC		-
338	Phosphorylation	DDITSLVTDTTLLVH HHHHHHHCCCCHHHH		-
521	Phosphorylation	QKYPTFKSCLKKELH HHCCCHHHHHHHHHH		27135362

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MICU3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MICU3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MICU3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MICU3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.