| UniProt ID | MIC25_MOUSE | |
|---|---|---|
| UniProt AC | Q91VN4 | |
| Protein Name | MICOS complex subunit Mic25 | |
| Gene Name | Chchd6 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 273 | |
| Subcellular Localization |
Mitochondrion inner membrane Lipid-anchor . Mitochondrion . |
|
| Protein Description | Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.. | |
| Protein Sequence | MGSAESAEARRVSFEMDEEERVRVLQGIRLSESVVNRMKDCSQPSAGEQLVPGFGPSSSAPVPTVPLPAISVPTVPAPTTPVPTAPSSSVRGLPGGTCKGPLTDVKVPSAESGGGLQSSAVKEDLKKFQQEQLAVQDEMVRVAKKEKEAAEKHLKASLPKKKASLTHEQQQSARLARELEDREAELSRRDTFYKEQQGRIQEKNAELYKLSSQQFHEAASKAESTIKPRRVEPVCSGLQAQILRCYRDHLHEVLLCSDLVKAYQHCVSTARKG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Myristoylation | ------MGSAESAEA ------CCCHHHHHH | - | ||
| 13 | Phosphorylation | SAEARRVSFEMDEEE HHHHHHCCCCCCHHH | 25521595 | ||
| 31 | Phosphorylation | VLQGIRLSESVVNRM HHHHHHCCHHHHHHC | 22817900 | ||
| 33 | Phosphorylation | QGIRLSESVVNRMKD HHHHCCHHHHHHCCC | 25521595 | ||
| 103 | Phosphorylation | GTCKGPLTDVKVPSA CCCCCCCCCCCCCCC | 25777480 | ||
| 109 | Phosphorylation | LTDVKVPSAESGGGL CCCCCCCCCCCCCCC | 25777480 | ||
| 112 | Phosphorylation | VKVPSAESGGGLQSS CCCCCCCCCCCCCCH | 28066266 | ||
| 118 | Phosphorylation | ESGGGLQSSAVKEDL CCCCCCCCHHHHHHH | 25777480 | ||
| 119 | Phosphorylation | SGGGLQSSAVKEDLK CCCCCCCHHHHHHHH | 25777480 | ||
| 157 | Phosphorylation | AEKHLKASLPKKKAS HHHHHHHHCCHHHHC | 27681418 | ||
| 164 | Phosphorylation | SLPKKKASLTHEQQQ HCCHHHHCCCHHHHH | 26824392 | ||
| 166 | Phosphorylation | PKKKASLTHEQQQSA CHHHHCCCHHHHHHH | 30635358 | ||
| 194 | Ubiquitination | SRRDTFYKEQQGRIQ HHHHHHHHHHHHCHH | 22790023 | ||
| 194 | Ubiquitination | SRRDTFYKEQQGRIQ HHHHHHHHHHHHCHH | 22790023 | ||
| 220 | Phosphorylation | QQFHEAASKAESTIK HHHHHHHHHCHHCCC | - | ||
| 220 | O-linked_Glycosylation | QQFHEAASKAESTIK HHHHHHHHHCHHCCC | 9841279 | ||
| 236 | Phosphorylation | RRVEPVCSGLQAQIL CCCHHCCCHHHHHHH | 29899451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MIC25_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MIC25_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MIC25_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MIC25_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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