MGST3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MGST3_MOUSE
• UniProt AC: Q9CPU4
• Protein Name: Microsomal glutathione S-transferase 3
• Gene Name: Mgst3
• Organism: Mus musculus (Mouse).
• Sequence Length: 153
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein . Microsome membrane ; Multi-pass membrane protein . Microsome membrane ; Lipid-anchor .
• Protein Description: Also functions as a glutathione peroxidase..
• Protein Sequence: MAVLSKEYGFVLLTGAASFVMVLHLAINVGKARKKYKVEYPVMYSTDPENGHMFNCIQRAHQNTLEVYPPFLFFLTVGGVYHPRIASGLGLAWIIGRVLYAYGYYTGDPSKRYRGAVGSLALFALMGTTVCSAFQHLGWIRPGLGYGSRSCHH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Ubiquitination	GKARKKYKVEYPVMY CHHCCCEEEEEEEEE	37.15	22790023
56	S-nitrosocysteine	ENGHMFNCIQRAHQN CCCCCCHHHHHHHHC	1.59	-
56	Glutathionylation	ENGHMFNCIQRAHQN CCCCCCHHHHHHHHC	1.59	24333276
56	S-nitrosylation	ENGHMFNCIQRAHQN CCCCCCHHHHHHHHC	1.59	21278135
56	S-palmitoylation	ENGHMFNCIQRAHQN CCCCCCHHHHHHHHC	1.59	28680068
111	Acetylation	YYTGDPSKRYRGAVG CCCCCCCHHCCHHHH	59.86	15613451
151	S-palmitoylation	LGYGSRSCHH----- CCCCCCCCCC-----	3.09	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MGST3_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MGST3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MGST3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MGST3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.