MGAT2_HUMAN - dbPTM
MGAT2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MGAT2_HUMAN
UniProt AC Q10469
Protein Name Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Gene Name MGAT2
Organism Homo sapiens (Human).
Sequence Length 447
Subcellular Localization Golgi apparatus membrane
Single-pass type II membrane protein.
Protein Description Catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans..
Protein Sequence MRFRIYKRKVLILTLVVAACGFVLWSSNGRQRKNEALAPPLLDAEPARGAGGRGGDHPSVAVGIRRVSNVSAASLVPAVPQPEADNLTLRYRSLVYQLNFDQTLRNVDKAGTWAPRELVLVVQVHNRPEYLRLLLDSLRKAQGIDNVLVIFSHDFWSTEINQLIAGVNFCPVLQVFFPFSIQLYPNEFPGSDPRDCPRDLPKNAALKLGCINAEYPDSFGHYREAKFSQTKHHWWWKLHFVWERVKILRDYAGLILFLEEDHYLAPDFYHVFKKMWKLKQQECPECDVLSLGTYSASRSFYGMADKVDVKTWKSTEHNMGLALTRNAYQKLIECTDTFCTYDDYNWDWTLQYLTVSCLPKFWKVLVPQIPRIFHAGDCGMHHKKTCRPSTQSAQIESLLNNNKQYMFPETLTISEKFTVVAISPPRKNGGWGDIRDHELCKSYRRLQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
33UbiquitinationSSNGRQRKNEALAPP
CCCCCCCCCCCCCCC		51.2924816145
59O-linked_GlycosylationGRGGDHPSVAVGIRR
CCCCCCCCHHHEEEE		21.2055833699
68PhosphorylationAVGIRRVSNVSAASL
HHEEEEECCCCHHHH		29.6924719451
69N-linked_GlycosylationVGIRRVSNVSAASLV
HEEEEECCCCHHHHC		28.98UniProtKB CARBOHYD
71PhosphorylationIRRVSNVSAASLVPA
EEEECCCCHHHHCCC		23.5124719451
74O-linked_GlycosylationVSNVSAASLVPAVPQ
ECCCCHHHHCCCCCC		29.62OGP
86N-linked_GlycosylationVPQPEADNLTLRYRS
CCCCCCCCEEEEEHH		41.8129666272
88PhosphorylationQPEADNLTLRYRSLV
CCCCCCEEEEEHHHH		18.5524719451
137PhosphorylationYLRLLLDSLRKAQGI
HHHHHHHHHHHHCCC		30.0026091039
207UbiquitinationLPKNAALKLGCINAE
CCCCHHHHHCCCCCC		37.8029967540
215PhosphorylationLGCINAEYPDSFGHY
HCCCCCCCCCCCCCC		15.2129759185
226UbiquitinationFGHYREAKFSQTKHH
CCCCCEECCCCCCCC		40.5729967540
301PhosphorylationYSASRSFYGMADKVD
CCCCCCCCCCCCCCC		13.77-
306UbiquitinationSFYGMADKVDVKTWK
CCCCCCCCCCCCCCC		30.69-
311PhosphorylationADKVDVKTWKSTEHN
CCCCCCCCCCCCCCH		37.6624719451
356PhosphorylationTLQYLTVSCLPKFWK
EEHHEEHHHCHHHHH		12.52-
385O-linked_GlycosylationCGMHHKKTCRPSTQS
CCCCCCCCCCCCCCH		20.67OGP
389PhosphorylationHKKTCRPSTQSAQIE
CCCCCCCCCCHHHHH		21.52-
389O-linked_GlycosylationHKKTCRPSTQSAQIE
CCCCCCCCCCHHHHH		21.52OGP
390O-linked_GlycosylationKKTCRPSTQSAQIES
CCCCCCCCCHHHHHH		29.26OGP
423PhosphorylationKFTVVAISPPRKNGG
CEEEEEECCCCCCCC		21.0827486199
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MGAT2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MGAT2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MGAT2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MGAT2_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MGAT2_HUMAN

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Related Literatures of Post-Translational Modification

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