MFSD1_HUMAN - dbPTM
MFSD1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MFSD1_HUMAN
UniProt AC Q9H3U5
Protein Name Major facilitator superfamily domain-containing protein 1
Gene Name MFSD1
Organism Homo sapiens (Human).
Sequence Length 465
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description
Protein Sequence MEEEDEEARALLAGGPDEADRGAPAAPGALPALCDPSRLAHRLLVLLLMCFLGFGSYFCYDNPAALQTQVKRDMQVNTTKFMLLYAWYSWPNVVLCFFGGFLIDRVFGIRWGTIIFSCFVCIGQVVFALGGIFNAFWLMEFGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKIEALLGSAGHTTLGITLMIGGITCILSLICALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAVFPFIGLGKVFFTEKFGFSSQAASAINSVVYVISAPMSPVFGLLVDKTGKNIIWVLCAVAATLVSHMMLAFTMWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAIISIIAGMILDSRGYLFLEVFFIACVSLSLLSVVLLYLVNRAQGGNLNYSARQREEIKFSHTE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
148UbiquitinationFGRFVFGIGGESLAV
HCCEEEECCCCHHHH		4.3233845483
152UbiquitinationVFGIGGESLAVAQNT
EEECCCCHHHHHCCE		25.5523000965
158UbiquitinationESLAVAQNTYAVSWF
CHHHHHCCEEEEEEE		25.8923000965
163UbiquitinationAQNTYAVSWFKGKEL
HCCEEEEEEECCCHH		20.7223000965
172UbiquitinationFKGKELNLVFGLQLS
ECCCHHEEEEEEEEH		5.4433845483
176 (in isoform 4)Ubiquitination-2.9221890473
176UbiquitinationELNLVFGLQLSMARI
HHEEEEEEEEHHHHH		2.9223000965
179PhosphorylationLVFGLQLSMARIGST
EEEEEEEHHHHHCCC		9.4630619164
182 (in isoform 4)Ubiquitination-25.7621890473
182UbiquitinationGLQLSMARIGSTVNM
EEEEHHHHHCCCCCH		25.7623000965
187UbiquitinationMARIGSTVNMNLMGW
HHHHCCCCCHHHHHH		7.3823000965
245UbiquitinationRAERILHKEQGKTGE
HHHHHHHHHCCCCCC		48.57-
249UbiquitinationILHKEQGKTGEVIKL
HHHHHCCCCCCEEEE		53.7221890473
249 (in isoform 1)Ubiquitination-53.7221890473
255 (in isoform 1)Ubiquitination-50.9721890473
255UbiquitinationGKTGEVIKLTDVKDF
CCCCCEEEECCCCCC		50.972189047
259UbiquitinationEVIKLTDVKDFSLPL
CEEEECCCCCCCHHH		5.5921890473
259 (in isoform 3)Ubiquitination-5.5921890473
259UbiquitinationEVIKLTDVKDFSLPL
CEEEECCCCCCCHHH		5.5921890473
265UbiquitinationDVKDFSLPLWLIFII
CCCCCCHHHHHHHHH		21.9421890473
265 (in isoform 3)Ubiquitination-21.9421890473
265UbiquitinationDVKDFSLPLWLIFII
CCCCCCHHHHHHHHH		21.9421890473
270UbiquitinationSLPLWLIFIICVCYY
CHHHHHHHHHHHHHH		2.6323000965
294UbiquitinationGKVFFTEKFGFSSQA
CCCEEEECCCCCHHH		47.9727667366
298 (in isoform 4)Ubiquitination-23.1721890473
298UbiquitinationFTEKFGFSSQAASAI
EEECCCCCHHHHHHC		23.1721890473
304 (in isoform 4)Ubiquitination-10.5621890473
304UbiquitinationFSSQAASAINSVVYV
CCHHHHHHCCCEEEE		10.5621890473
309UbiquitinationASAINSVVYVISAPM
HHHCCCEEEEEECCC		2.9523000965
327PhosphorylationFGLLVDKTGKNIIWV
HHHHCCCCCCHHHHH		49.26-
363UbiquitinationWIAMCLLGLSYSLLA
HHHHHHHHHHHHHHH		10.3023000965
387UbiquitinationVVPEHQLGTAYGFMQ
EECHHHHHHHHHHHH		11.1723000965
387 (in isoform 4)Ubiquitination-11.1721890473
460 (in isoform 1)Ubiquitination-44.0621890473
460UbiquitinationARQREEIKFSHTE--
HHHHHCCCCCCCC--		44.06-
470UbiquitinationHTE------------
CCC------------		21890473
470UbiquitinationHTE------------
CCC------------		21890473
470 (in isoform 3)Ubiquitination-21890473
509Ubiquitination---------------------------------------------------
---------------------------------------------------		21890473
509 (in isoform 4)Ubiquitination-21890473
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MFSD1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MFSD1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MFSD1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MFSD1_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MFSD1_HUMAN

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Related Literatures of Post-Translational Modification

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