| UniProt ID | MFS12_HUMAN | |
|---|---|---|
| UniProt AC | Q6NUT3 | |
| Protein Name | Major facilitator superfamily domain-containing protein 12 | |
| Gene Name | MFSD12 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 480 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | ||
| Protein Sequence | MGPGPPAAGAAPSPRPLSLVARLSYAVGHFLNDLCASMWFTYLLLYLHSVRAYSSRGAGLLLLLGQVADGLCTPLVGYEADRAASCCARYGPRKAWHLVGTVCVLLSFPFIFSPCLGCGAATPEWAALLYYGPFIVIFQFGWASTQISHLSLIPELVTNDHEKVELTALRYAFTVVANITVYGAAWLLLHLQGSSRVEPTQDISISDQLGGQDVPVFRNLSLLVVGVGAVFSLLFHLGTRERRRPHAEEPGEHTPLLAPATAQPLLLWKHWLREPAFYQVGILYMTTRLIVNLSQTYMAMYLTYSLHLPKKFIATIPLVMYLSGFLSSFLMKPINKCIGRNMTYFSGLLVILAFAAWVALAEGLGVAVYAAAVLLGAGCATILVTSLAMTADLIGPHTNSGAFVYGSMSFLDKVANGLAVMAIQSLHPCPSELCCRACVSFYHWAMVAVTGGVGVAAALCLCSLLLWPTRLRRWDRDARP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MGPGPPAA -------CCCCCCCC | 15.32 | 25732826 | |
| 13 | Phosphorylation | PAAGAAPSPRPLSLV CCCCCCCCCCCHHHH | 28.90 | 29255136 | |
| 86 | S-palmitoylation | EADRAASCCARYGPR CHHHHHHHHHHHCCH | 1.48 | 29575903 | |
| 87 | S-palmitoylation | ADRAASCCARYGPRK HHHHHHHHHHHCCHH | 1.93 | 29575903 | |
| 151 | Phosphorylation | STQISHLSLIPELVT HHHHHHHHHCHHHHC | 20.87 | 27732954 | |
| 158 | Phosphorylation | SLIPELVTNDHEKVE HHCHHHHCCCHHHHH | 47.77 | 27732954 | |
| 167 | Phosphorylation | DHEKVELTALRYAFT CHHHHHHHHHHHHHH | 15.33 | 24719451 | |
| 200 | O-linked_Glycosylation | GSSRVEPTQDISISD CCCCCCCCCCCCHHH | 25.93 | OGP | |
| 254 | Phosphorylation | AEEPGEHTPLLAPAT CCCCCCCCCCCCCCC | 16.01 | 25850435 | |
| 440 | Phosphorylation | LCCRACVSFYHWAMV HHHHHHHHHHHHHHH | 21.70 | 22210691 | |
| 450 | Phosphorylation | HWAMVAVTGGVGVAA HHHHHHHHCCHHHHH | 20.62 | 22210691 | |
| 469 | Phosphorylation | CSLLLWPTRLRRWDR HHHHHHHHHHHHCCC | 30.65 | 22210691 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MFS12_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MFS12_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MFS12_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MFS12_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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