MFS11_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MFS11_HUMAN
• UniProt AC: O43934
• Protein Name: UNC93-like protein MFSD11
• Gene Name: MFSD11
• Organism: Homo sapiens (Human).
• Sequence Length: 449
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNRTDFHGSGYTSMAIIYGVFSASNLITPSVVAIVGPQLSMFASGLFYSMYIAVFIQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHSIGRNSGIFWALLQSSLFFGNLYIYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLGEDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTGLELTFFSGVYGTCIGATNKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLSKNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTISFFTVEWEAAAFVARGSDYRSI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	N-linked_Glycosylation	QTVIRSLNRTDFHGS HHHHHHCCCCCCCCC	46.16	UniProtKB CARBOHYD
195	Phosphorylation	FLIRKPDSENVLGED HHCCCCCCCCCCCCC	39.33	27732954
204	Phosphorylation	NVLGEDESSDDQDME CCCCCCCCCCCCCHH	51.92	30576142
205	Phosphorylation	VLGEDESSDDQDMEV CCCCCCCCCCCCHHH	43.06	30576142
215	Phosphorylation	QDMEVNESAQNNLTK CCHHHCHHHHHHHHH	29.92	27732954
300	Phosphorylation	GSLFGLLSKNNRFGR HHHHHHHHCCCCCCC	38.08	24719451
348	Ubiquitination	TDSSAYIKSSKEVAI CCCCCCCCCHHHHHH	35.68	-
448	Phosphorylation	ARGSDYRSI------ HCCCCCCCC------	26.81	21712546

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MFS11_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MFS11_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MFS11_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SMAP2_HUMAN	SMAP2	physical	28514442
UB2Q1_HUMAN	UBE2Q1	physical	28514442
TBB1_HUMAN	TUBB1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.