dbPTM

MFS10_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MFS10_MOUSE
UniProt AC	Q9D2V8
Protein Name	Major facilitator superfamily domain-containing protein 10
Gene Name	Mfsd10
Organism	Mus musculus (Mouse).
Sequence Length	456
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump (By similarity)..
Protein Sequence	MGWAGDAGCTPRPPIRPRPASERRVIIVLFLGLLLDLLAFTLLLPLLPGLLERHGREQDPLYGSWQRGVDWFASAIGMPAEKRYNSVLFGGLIGSAFSLLQFFSAPLTGAASDYLGRRPVMMLSLTGLAISYAVWATSRSFKAFLASRVIGGISKGNVNLSTAIVADLGSPPTRSQGMAVIGVAFSLAFTLGPMLGAFLSVEMVPWISLLFAISDMLFIFCFLPETLPQEKRASSVTLGFHTAAHLLSPLALLRFAAVTHSQDPPAEHRLRNLRRLGLVYFLYLFLFSGLEYTLSFLAHQRFQFSSLQQGKMFFFIGLTMATIQGTYARRISPGKEAAAVTRAMLLLVPAFLLIGWAHSLPTLGLGLMLYSFAAAVVVPGLSTMVSSYGSPGQKGTIMGILRSLGALGRALGPVVAASVYWLTGAQVCFTVCSALFLLPFLLLWKLKHPAETSKEE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
159	N-linked_Glycosylation	GISKGNVNLSTAIVA CCCCCCCCCCHHHEE	32.07	-
322	Phosphorylation	FIGLTMATIQGTYAR EEEEHHHHHCHHCHH	11.74	29899451
326	Phosphorylation	TMATIQGTYARRISP HHHHHCHHCHHHCCC	9.53	29899451
332	Phosphorylation	GTYARRISPGKEAAA HHCHHHCCCCHHHHH	26.28	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MFS10_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MFS10_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MFS10_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MFS10_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MFS10_MOUSE

Related Literatures of Post-Translational Modification