MFAP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MFAP2_HUMAN
• UniProt AC: P55001
• Protein Name: Microfibrillar-associated protein 2
• Gene Name: MFAP2
• Organism: Homo sapiens (Human).
• Sequence Length: 183
• Subcellular Localization: Secreted, extracellular space, extracellular matrix.
• Protein Description: Component of the elastin-associated microfibrils..
• Protein Sequence: MRAAYLFLLFLPAGLLAQGQYDLDPLPPFPDHVQYTHYSDQIDNPDYYDYQEVTPRPSEEQFQFQSQQQVQQEVIPAPTPEPGNAELEPTEPGPLDCREEQYPCTRLYSIHRPCKQCLNEVCFYSLRRVYVINKEICVRTVCAHEELLRADLCRDKFSKCGVMASSGLCQSVAASCARSCGSC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Pyrrolidone_carboxylic_acid	LPAGLLAQGQYDLDP HHHHHHHCCCCCCCC	39.22	-
18	Pyrrolidone_carboxylic_acid	LPAGLLAQGQYDLDP HHHHHHHCCCCCCCC	39.22	-
47	Sulfation	DQIDNPDYYDYQEVT CCCCCCCCCCCCCCC	10.25	11284693
47	Sulfation	DQIDNPDYYDYQEVT CCCCCCCCCCCCCCC	10.25	-
48	Sulfation	QIDNPDYYDYQEVTP CCCCCCCCCCCCCCC	18.63	11284693
48	Sulfation	QIDNPDYYDYQEVTP CCCCCCCCCCCCCCC	18.63	-
50	Sulfation	DNPDYYDYQEVTPRP CCCCCCCCCCCCCCC	7.17	11284693
50	Sulfation	DNPDYYDYQEVTPRP CCCCCCCCCCCCCCC	7.17	-
54	O-linked_Glycosylation	YYDYQEVTPRPSEEQ CCCCCCCCCCCCHHH	16.90	11284693
54	O-linked_Glycosylation	YYDYQEVTPRPSEEQ CCCCCCCCCCCCHHH	16.90	11284693
79	O-linked_Glycosylation	QEVIPAPTPEPGNAE CCCCCCCCCCCCCCC	42.25	11284693
79	O-linked_Glycosylation	QEVIPAPTPEPGNAE CCCCCCCCCCCCCCC	42.25	11284693
90	O-linked_Glycosylation	GNAELEPTEPGPLDC CCCCCCCCCCCCCCC	45.49	11284693
90	O-linked_Glycosylation	GNAELEPTEPGPLDC CCCCCCCCCCCCCCC	45.49	11284693
109	Phosphorylation	YPCTRLYSIHRPCKQ CCCCCCEECCHHHHH	19.26	30631047
125	Phosphorylation	LNEVCFYSLRRVYVI HHHHHHHHHEEEEEE	8.64	24719451
165	Phosphorylation	SKCGVMASSGLCQSV HHHCCHHCCCHHHHH	13.57	-
175	Phosphorylation	LCQSVAASCARSCGS HHHHHHHHHHHHCCC	9.89	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MFAP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MFAP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MFAP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PGS1_HUMAN	BGN	physical	11723132
CO4A3_HUMAN	COL4A3	physical	9278443

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.