MF14B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MF14B_HUMAN
• UniProt AC: Q5SR56
• Protein Name: Hippocampus abundant transcript-like protein 1 {ECO:0000312|HGNC:HGNC:23376}
• Gene Name: MFSD14B {ECO:0000312|HGNC:HGNC:23376}
• Organism: Homo sapiens (Human).
• Sequence Length: 506
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MSVEPPPELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGRPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFAMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDICFILVAVPESLPEKMRPVSWGAQISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYMFHVELTELGPKLNSNNVPLQGAVIPGPPFLFGACIVLMSFLVALFIPEYSKASGVQKHSNSSSGSLTNTPERGSDEDIEPLLQDSSIWELSSFEEPGNQCTEL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSVEPPPEL ------CCCCCCHHH		25850435
15	Phosphorylation	ELEEKAASEPEAGAM HHHHHHHCCCCCCCC		25159151
25	Ubiquitination	EAGAMPEKRAGAQAA CCCCCCHHHHHCCCC		22817900
77	Ubiquitination	LHETFSQHTFLMNGL HHHHHHHHHHHHHHH		21963094
78	Ubiquitination	HETFSQHTFLMNGLI HHHHHHHHHHHHHHH		22817900
81	Ubiquitination	FSQHTFLMNGLIQGV HHHHHHHHHHHHHHH		22817900
181	Ubiquitination	TFAASLVSSPAIGAY HHHHHHCCCHHHHHH		21963094
181	Ubiquitination	TFAASLVSSPAIGAY HHHHHHCCCHHHHHH		21906983
182	Ubiquitination	FAASLVSSPAIGAYL HHHHHCCCHHHHHHH		-
182	Ubiquitination	FAASLVSSPAIGAYL HHHHHCCCHHHHHHH		22817900
185	Ubiquitination	SLVSSPAIGAYLSAS HHCCCHHHHHHHHHH		22817900
246	Ubiquitination	ADPFASLKKVGKDST CCCCHHHHHCCCCHH		21906983
247	Ubiquitination	DPFASLKKVGKDSTV CCCHHHHHCCCCHHH		22817900
250	Ubiquitination	ASLKKVGKDSTVLLI HHHHHCCCCHHHHHH		22817900
291	Ubiquitination	GFGSVKIAAFIAMVG CCCHHHHHHHHHHHH		22817900
383	Phosphorylation	GVAQGIITGIRGLCN HHHHHHHHHHHHHHC		24719451
387	Ubiquitination	GIITGIRGLCNGLGP HHHHHHHHHHCCHHH		22817900
395	Ubiquitination	LCNGLGPALYGFIFY HHCCHHHHHHHHHHH		22817900
460	Ubiquitination	SKASGVQKHSNSSSG HHHCCCCCCCCCCCC		21906983
462	Phosphorylation	ASGVQKHSNSSSGSL HCCCCCCCCCCCCCC		30108239
463	N-linked_Glycosylation	SGVQKHSNSSSGSLT CCCCCCCCCCCCCCC		UniProtKB CARBOHYD
464	Phosphorylation	GVQKHSNSSSGSLTN CCCCCCCCCCCCCCC		28450419
465	Phosphorylation	VQKHSNSSSGSLTNT CCCCCCCCCCCCCCC		25849741
466	Phosphorylation	QKHSNSSSGSLTNTP CCCCCCCCCCCCCCC		30108239
468	Phosphorylation	HSNSSSGSLTNTPER CCCCCCCCCCCCCCC		25849741
470	Phosphorylation	NSSSGSLTNTPERGS CCCCCCCCCCCCCCC		30108239
472	Phosphorylation	SSGSLTNTPERGSDE CCCCCCCCCCCCCCC		30108239

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MF14B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MF14B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MF14B_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MF14B_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.