MF14A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MF14A_HUMAN
• UniProt AC: Q96MC6
• Protein Name: Hippocampus abundant transcript 1 protein {ECO:0000312|HGNC:HGNC:23363}
• Gene Name: MFSD14A {ECO:0000312|HGNC:HGNC:23363}
• Organism: Homo sapiens (Human).
• Sequence Length: 490
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MTQGKKKKRAANRSIMLAKKIIIKDGGTPQGIGSPSVYHAVIVIFLEFFAWGLLTAPTLVVLHETFPKHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKSFLLLTVFFTCAPIPLMKISPWWYFAVISVSGVFAVTFSVVFAYVADITQEHERSMAYGLVSATFAASLVTSPAIGAYLGRVYGDSLVVVLATAIALLDICFILVAVPESLPEKMRPASWGAPISWEQADPFASLKKVGQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGILSIIAQTIVLSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSITFPAVSALVSRTADADQQGVVQGMITGIRGLCNGLGPALYGFIFYIFHVELKELPITGTDLGTNTSPQHHFEQNSIIPGPPFLFGACSVLLALLVALFIPEHTNLSLRSSSWRKHCGSHSHPHNTQAPGEAKEPLLQDTNV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MTQGKKKK -------CCCCHHHH		25732826
12	N-linked_Glycosylation	KKKKRAANRSIMLAK HHHHHHHHHHHHEEE		UniProtKB CARBOHYD
14	Phosphorylation	KKRAANRSIMLAKKI HHHHHHHHHHEEEEE		28857561
157	Phosphorylation	ITQEHERSMAYGLVS HCHHHHHHHHHHHHH		25907765
160	Phosphorylation	EHERSMAYGLVSATF HHHHHHHHHHHHHHH		25907765
164	Phosphorylation	SMAYGLVSATFAASL HHHHHHHHHHHHHHH		25907765
166	Phosphorylation	AYGLVSATFAASLVT HHHHHHHHHHHHHHC		25907765
170	Phosphorylation	VSATFAASLVTSPAI HHHHHHHHHHCCHHH		25907765
173	Phosphorylation	TFAASLVTSPAIGAY HHHHHHHCCHHHHHH		25907765
174	Phosphorylation	FAASLVTSPAIGAYL HHHHHHCCHHHHHHH		25907765
180	Phosphorylation	TSPAIGAYLGRVYGD CCHHHHHHHHHHHCH		25907765
238	Ubiquitination	ADPFASLKKVGQDSI CCCCHHHHHHCHHHH		29967540
375	Phosphorylation	GVVQGMITGIRGLCN HHHHHHHHHHHHHHC		24719451
453	N-linked_Glycosylation	LFIPEHTNLSLRSSS HHCCCCCCCCCCCCH		UniProtKB CARBOHYD
463	Ubiquitination	LRSSSWRKHCGSHSH CCCCHHHHHCCCCCC		-
467	Phosphorylation	SWRKHCGSHSHPHNT HHHHHCCCCCCCCCC		28270605
469	Phosphorylation	RKHCGSHSHPHNTQA HHHCCCCCCCCCCCC		28270605
474	Phosphorylation	SHSHPHNTQAPGEAK CCCCCCCCCCCCCCC		24719451
481	Ubiquitination	TQAPGEAKEPLLQDT CCCCCCCCCCCCCCC		33845483

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MF14A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MF14A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MF14A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MF14A_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.