| UniProt ID | METL5_HUMAN | |
|---|---|---|
| UniProt AC | Q9NRN9 | |
| Protein Name | Methyltransferase-like protein 5 | |
| Gene Name | METTL5 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 209 | |
| Subcellular Localization | ||
| Protein Description | Probable methyltransferase.. | |
| Protein Sequence | MKKVRLKELESRLQQVDGFEKPKLLLEQYPTRPHIAACMLYTIHNTYDDIENKVVADLGCGCGVLSIGTAMLGAGLCVGFDIDEDALEIFNRNAEEFELTNIDMVQCDVCLLSNRMSKSFDTVIMNPPFGTKNNKGTDMAFLKTALEMARTAVYSLHKSSTREHVQKKAAEWKIKIDIIAELRYDLPASYKFHKKKSVDIEVDLIRFSF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Ubiquitination | -MKKVRLKELESRLQ -CCCHHHHHHHHHHH | 50.08 | 27667366 | |
| 21 | Ubiquitination | QQVDGFEKPKLLLEQ HHCCCCCCCHHHHHH | 45.23 | 21906983 | |
| 23 | Ubiquitination | VDGFEKPKLLLEQYP CCCCCCCHHHHHHCC | 63.94 | 23503661 | |
| 118 | Ubiquitination | LLSNRMSKSFDTVIM HHHCCCCCCCCEEEE | 45.88 | 21890473 | |
| 119 | Phosphorylation | LSNRMSKSFDTVIMN HHCCCCCCCCEEEEC | 22.50 | 19845377 | |
| 122 | Phosphorylation | RMSKSFDTVIMNPPF CCCCCCCEEEECCCC | 15.21 | 19845377 | |
| 131 | Phosphorylation | IMNPPFGTKNNKGTD EECCCCCCCCCCCCC | 30.86 | 29083192 | |
| 132 | Ubiquitination | MNPPFGTKNNKGTDM ECCCCCCCCCCCCCH | 59.92 | 21906983 | |
| 135 | Ubiquitination | PFGTKNNKGTDMAFL CCCCCCCCCCCHHHH | 73.00 | 23503661 | |
| 143 | Ubiquitination | GTDMAFLKTALEMAR CCCHHHHHHHHHHHH | 25.87 | 2190698 | |
| 144 | Phosphorylation | TDMAFLKTALEMART CCHHHHHHHHHHHHH | 38.33 | 22210691 | |
| 154 | Phosphorylation | EMARTAVYSLHKSST HHHHHHHHHHHHHCC | 11.75 | 29496907 | |
| 158 | Ubiquitination | TAVYSLHKSSTREHV HHHHHHHHHCCHHHH | 51.93 | 29967540 | |
| 160 | Phosphorylation | VYSLHKSSTREHVQK HHHHHHHCCHHHHHH | 35.97 | 22210691 | |
| 161 | Phosphorylation | YSLHKSSTREHVQKK HHHHHHCCHHHHHHH | 47.36 | 22210691 | |
| 175 | Acetylation | KAAEWKIKIDIIAEL HHHHHEEEEEEEEHH | 30.51 | 19667077 | |
| 191 | Acetylation | YDLPASYKFHKKKSV CCCCCCCCCCCCCCC | 38.20 | 23236377 | |
| 191 | Ubiquitination | YDLPASYKFHKKKSV CCCCCCCCCCCCCCC | 38.20 | 21890473 | |
| 195 | Acetylation | ASYKFHKKKSVDIEV CCCCCCCCCCCCEEE | 41.53 | 19667085 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of METL5_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of METL5_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of METL5_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of METL5_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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