| UniProt ID | METE1_ARATH | |
|---|---|---|
| UniProt AC | O50008 | |
| Protein Name | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | |
| Gene Name | MS1 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 765 | |
| Subcellular Localization | Cytoplasm, cytosol . | |
| Protein Description | Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.. | |
| Protein Sequence | MASHIVGYPRMGPKRELKFALESFWDGKSTAEDLQKVSADLRSSIWKQMSAAGTKFIPSNTFAHYDQVLDTTAMLGAVPPRYGYTGGEIGLDVYFSMARGNASVPAMEMTKWFDTNYHYIVPELGPEVNFSYASHKAVNEYKEAKALGVDTVPVLVGPVSYLLLSKAAKGVDKSFELLSLLPKILPIYKEVITELKAAGATWIQLDEPVLVMDLEGQKLQAFTGAYAELESTLSGLNVLVETYFADIPAEAYKTLTSLKGVTAFGFDLVRGTKTLDLVKAGFPEGKYLFAGVVDGRNIWANDFAASLSTLQALEGIVGKDKLVVSTSCSLLHTAVDLINETKLDDEIKSWLAFAAQKVVEVNALAKALAGQKDEALFSANAAALASRRSSPRVTNEGVQKAAAALKGSDHRRATNVSARLDAQQKKLNLPILPTTTIGSFPQTVELRRVRREYKAKKVSEEDYVKAIKEEIKKVVDLQEELDIDVLVHGEPERNDMVEYFGEQLSGFAFTANGWVQSYGSRCVKPPVIYGDVSRPKAMTVFWSAMAQSMTSRPMKGMLTGPVTILNWSFVRNDQPRHETCYQIALAIKDEVEDLEKGGIGVIQIDEAALREGLPLRKSEHAFYLDWAVHSFRITNCGVQDSTQIHTHMCYSHFNDIIHSIIDMDADVITIENSRSDEKLLSVFREGVKYGAGIGPGVYDIHSPRIPSSEEIADRVNKMLAVLEQNILWVNPDCGLKTRKYTEVKPALKNMVDAAKLIRSQLASAK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASHIVGYPR -----CCCCCCCCCC | 25561503 | ||
| 38 | Phosphorylation | AEDLQKVSADLRSSI HHHHHHHCHHHHHHH | 30291188 | ||
| 49 | Sulfoxidation | RSSIWKQMSAAGTKF HHHHHHHHHHHCCCC | 25693801 | ||
| 103 | Phosphorylation | SMARGNASVPAMEMT EHHCCCCCCCHHHHE | 23111157 | ||
| 279 | Acetylation | TKTLDLVKAGFPEGK CCHHHHHHCCCCCCC | 24727099 | ||
| 349 | Phosphorylation | KLDDEIKSWLAFAAQ CCCHHHHHHHHHHHH | 19880383 | ||
| 406 | Ubiquitination | QKAAAALKGSDHRRA HHHHHHHCCCHHHHH | - | ||
| 408 | Phosphorylation | AAAALKGSDHRRATN HHHHHCCCHHHHHCC | 29654922 | ||
| 459 | Phosphorylation | EYKAKKVSEEDYVKA HHHCCCCCHHHHHHH | 25561503 | ||
| 681 | Phosphorylation | RSDEKLLSVFREGVK CCCHHHHHHHHHHHC | 29654922 | ||
| 698 | Phosphorylation | AGIGPGVYDIHSPRI CCCCCCCEECCCCCC | 23776212 | ||
| 702 | Phosphorylation | PGVYDIHSPRIPSSE CCCEECCCCCCCCHH | 30291188 | ||
| 750 | Sulfoxidation | VKPALKNMVDAAKLI HHHHHHHHHHHHHHH | 25693801 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of METE1_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of METE1_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of METE1_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of METE1_ARATH !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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