MEST_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MEST_MOUSE
• UniProt AC: Q07646
• Protein Name: Mesoderm-specific transcript protein
• Gene Name: Mest
• Organism: Mus musculus (Mouse).
• Sequence Length: 335
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Sequence: MVRRDRLRRMREWWVQVGLLAVPLLAAYLHIPPPQLSPALHSWKTSGKFFTYKGLRIFYQDSVGVVGSPEIVVLLHGFPTSSYDWYKIWEGLTLRFHRVIALDFLGFGFSDKPRPHQYSIFEQASIVESLLRHLGLQNRRINLLSHDYGDIVAQELLYRYKQNRSGRLTIKSLCLSNGGIFPETHRPLLLQKLLKDGGVLSPILTRLMNFFVFSRGLTPVFGPYTRPTESELWDMWAVIRNNDGNLVIDSLLQYINQRKKFRRRWVGALASVSIPIHFIYGPLDPINPYPEFLELYRKTLPRSTVSILDDHISHYPQLEDPMGFLNAYMGFINSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
45	Phosphorylation	PALHSWKTSGKFFTY HHHCCCCCCCCCEEE	36.13	24719451
52	Phosphorylation	TSGKFFTYKGLRIFY CCCCCEEEEEEEEEE	9.63	24719451
163	N-linked_Glycosylation	LLYRYKQNRSGRLTI HHHHHHCCCCCCEEE	35.61	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MEST_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MEST_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MEST_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MEST_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.