MDL1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MDL1_SCHPO
• UniProt AC: Q9Y7M7
• Protein Name: ATP-dependent permease MDL1, mitochondrial
• Gene Name: mdl1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 726
• Subcellular Localization: Mitochondrion inner membrane ; Multi-pass membrane protein .
• Protein Description: Mediates export of peptides generated upon proteolysis of mitochondrial inner membrane proteins..
• Protein Sequence: MDPIRFGLSRVPFAHCYNKRVIFRANYLVPLTWLKNNVAYKSTNTLLLPTPNAEYYSTSKLSSQVNVSLNSLSQKASSGSKIYPFKNSFPLPFSRSILPIRSLAFLKLCVRHNSTVPSKDEQAQDISKINTNGTLQTPNKKVNVFRLFTLARGQGWNFFIAGSLLLVSSGVTMSIPYIVGKILDAGSSGDSSVTHIMGIPSGTFYIGLLGLFFLGSACNFGRIITLRLLSERIVSRLRARLFAKCMSLDGAFFDFHKHGDLISRLTTDSSIVGKSLSMYLSDGLRSSVSAIAGIGMMLYVSMRLTGYMSLIVPPIALGAFFYGEYVRKLSRTTQDALGDLTRVSEEKLANVRTTQAFLGERQEVNRYNDYIRNLFVLAKREAFASGIFFGSTGFLGNATVIAILALGGRMVAAGDITVGQLSSFLLYTVYAGGSIVGLSGCFTDIMKGLGAASRLFELLDAKPKIAPTVGIPVPVTVGKAILSFRNVGFAYPTRPSASIFDNLSFDIHPGTNVAIVAPSGGGKSTISQLLLRFYAPSSGKILADGVDISTYNVHQWRSHFGLVGQEPVLFSGTIGENIAYGKSNASQEEIEDAAKRANCSFVLSFPEKWSTQVGTRGLQLSGGQKQRIAIARALLRNPAFLILDEATSALDGEAEVMVDKTIQSLMHNRSMTTITIAHKLATIRRADQIIVVGDGKVLEQGSFERLSRPGTNFYKLMRWQLGKVEP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
66	N-linked_Glycosylation	SKLSSQVNVSLNSLS CCCHHCCCEEHHHHH		-
113	N-linked_Glycosylation	LKLCVRHNSTVPSKD HHHHHHCCCCCCCCC		-
132	N-linked_Glycosylation	DISKINTNGTLQTPN HHHCCCCCCCCCCCC		-
502	N-linked_Glycosylation	PSASIFDNLSFDIHP CCCCCCCCEEEEECC		-
584	N-linked_Glycosylation	NIAYGKSNASQEEIE CCCCCCCCCCHHHHH		-
598	N-linked_Glycosylation	EDAAKRANCSFVLSF HHHHHHCCCEEEEEC		-
668	N-linked_Glycosylation	TIQSLMHNRSMTTIT HHHHHHCCCCCCHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MDL1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MDL1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MDL1_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of MDL1_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.