dbPTM

MDE10_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MDE10_SCHPO
UniProt AC	O13766
Protein Name	Zinc metalloprotease mde10
Gene Name	mde10
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	512
Subcellular Localization	Endoplasmic reticulum. Spore wall. Endoplasmic reticulum during meiosis. Located at the spore rim at the end of meiosis.
Protein Description	Has a role in the development of the spore envelope..
Protein Sequence	MRLVLLFSCVLAVSSYAEIILAHSDENLLSRTKNNLSKWNENRLYDYGSKSTMSLPVSSLFPALQTLWIGVVADCSYVTHFTSRMEAKKHIFQEFEGVSTLYEDSFNINVQIHSLILPSAHDCSANVVDRPEISMSPRISIEEKLEIFSKWKYESPGNNVFEAISPHERESFPSEPQVSVLFTSSVKRSPHGVSWFATICSETHIENEWHVGPLSVVSAYPNDRLVVAHEIGHILGLIHDCNKKSCGDHSEACCPLSSSLCDAQELYIMNPSNSYTYANLRFSDCSILQLHSLVEKKYVSLSCLSKPSEKSVLRLGTCGNGIVEDGEECDCGEDCENNPCCDGKTCKLTKGSLCDDQQDACCYQCHFKNAGTLCRQSTNPCDKPEFCTGISSKCPVDENWDDGRICQDSLGMGSCASGVCTSASRQCKKLTNFSSLSCHSDSCKVSCQNEDGTCFISAKDYIDGTRCRGGLCYNGVCVPIEGSSASWSKQPSLFCASGTMLISLAVIAWFFW

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
35	N-linked_Glycosylation	LLSRTKNNLSKWNEN HHHHCCCCHHHCCCC	47.44	-
432	N-linked_Glycosylation	RQCKKLTNFSSLSCH HHHHHHCCCCCCEEC	45.28	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MDE10_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MDE10_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MDE10_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MDE10_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MDE10_SCHPO

Related Literatures of Post-Translational Modification