MCRI2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MCRI2_HUMAN
• UniProt AC: Q9BUT9
• Protein Name: MAPK regulated corepressor interacting protein 2
• Gene Name: MCRIP2
• Organism: Homo sapiens (Human).
• Sequence Length: 160
• Subcellular Localization: Cytoplasm, Stress granule . Nucleus .
• Protein Sequence: MYTITKGPSKLVAQRRTGPTQQQVEGRLGELLKCRQPAPPTSQPPRAQPFAQPPGPWPLSSPGPRLVFNRVNGRRAPSTSPSFEGTQETYTVAHEENVRFVSEAWQQVQQQLDGGPAGEGGPRPVQYVERTPNPRLQNFVPIDLDEWWAQQFLARITSCS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MYTITKGP -------CCEECCCH		22814378
2	Phosphorylation	------MYTITKGPS ------CCEECCCHH		27642862
10	Acetylation	TITKGPSKLVAQRRT EECCCHHHHEEECCC		25953088
17	Phosphorylation	KLVAQRRTGPTQQQV HHEEECCCCCCHHHH		28555341
35	Methylation	LGELLKCRQPAPPTS HHHHHHCCCCCCCCC		24129315
35	Dimethylation	LGELLKCRQPAPPTS HHHHHHCCCCCCCCC		-
60	Phosphorylation	PPGPWPLSSPGPRLV CCCCCCCCCCCCEEE		22199227
61	Phosphorylation	PGPWPLSSPGPRLVF CCCCCCCCCCCEEEE		21082442
65	Dimethylation	PLSSPGPRLVFNRVN CCCCCCCEEEEEEEC		-
65	Methylation	PLSSPGPRLVFNRVN CCCCCCCEEEEEEEC		24129315
70	Methylation	GPRLVFNRVNGRRAP CCEEEEEEECCEECC		-
78	Phosphorylation	VNGRRAPSTSPSFEG ECCEECCCCCCCCCC		23927012
79	Phosphorylation	NGRRAPSTSPSFEGT CCEECCCCCCCCCCC		23401153
80	Phosphorylation	GRRAPSTSPSFEGTQ CEECCCCCCCCCCCC		30266825
82	Phosphorylation	RAPSTSPSFEGTQET ECCCCCCCCCCCCCE		23927012
86	Phosphorylation	TSPSFEGTQETYTVA CCCCCCCCCCEEEEE		30266825
89	Phosphorylation	SFEGTQETYTVAHEE CCCCCCCEEEEECHH		23927012
90	Phosphorylation	FEGTQETYTVAHEEN CCCCCCEEEEECHHH		23927012
91	Phosphorylation	EGTQETYTVAHEENV CCCCCEEEEECHHHH		23927012

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MCRI2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MCRI2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MCRI2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1G_HUMAN	EEF1G	physical	16169070

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.