MCATL_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MCATL_MOUSE
• UniProt AC: Q8BL03
• Protein Name: Mitochondrial basic amino acids transporter
• Gene Name: Slc25a29
• Organism: Mus musculus (Mouse).
• Sequence Length: 306
• Subcellular Localization: Mitochondrion inner membrane ; Multi-pass membrane protein .
• Protein Description: Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. Does not transport carnitine nor acylcarnitines. Functions by both counter-exchange and uniport mechanisms (By similarity). Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15. [PubMed: 19287344]
• Protein Sequence: MALDFLAGCAGGVAGVIVGHPFDIVKVRLQVQSTEKPQYRGTLHCFQSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGQDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQAVGPARTYKGSLDCLVQIYRHEGLRGINRGMVSTLLRETPSFGVYFLTYDVMTRAMGCEPGDRLLVPKLLLAGGTSGITSWLSTYPMDVVKSRLQADGLQGTPRYRGIVDCMRQSYQAEGWQVFTRGLASTLLRAFPVNAATFATVTVVLTYTRGEEAQVDSEAALGTSPTPAGSALAQPSSL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
156	Phosphorylation	GINRGMVSTLLRETP CCCHHHHHHHHHHCC	12.40	26160508
157	Phosphorylation	INRGMVSTLLRETPS CCHHHHHHHHHHCCC	20.57	26160508
162	Phosphorylation	VSTLLRETPSFGVYF HHHHHHHCCCCEEEE	20.14	26160508
164	Phosphorylation	TLLRETPSFGVYFLT HHHHHCCCCEEEEEE	41.89	26160508
168	Phosphorylation	ETPSFGVYFLTYDVM HCCCCEEEEEEHHHH	8.02	26160508
171	Phosphorylation	SFGVYFLTYDVMTRA CCEEEEEEHHHHHHH	14.05	26160508
172	Phosphorylation	FGVYFLTYDVMTRAM CEEEEEEHHHHHHHC	14.53	26160508
176	Phosphorylation	FLTYDVMTRAMGCEP EEEHHHHHHHCCCCC	18.35	26160508

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MCATL_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MCATL_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MCATL_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of MCATL_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.