dbPTM

MCATL_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MCATL_HUMAN
UniProt AC	Q8N8R3
Protein Name	Mitochondrial basic amino acids transporter
Gene Name	SLC25A29
Organism	Homo sapiens (Human).
Sequence Length	303
Subcellular Localization	Mitochondrion inner membrane Multi-pass membrane protein .
Protein Description	Transports arginine, lysine, homoarginine, methylarginine and, to a much lesser extent, ornithine and histidine. [PubMed: 24652292 Can restore ornithine transport in cells lacking the primary mitochondrial ornithine transporter SLC25A15]
Protein Sequence	MALDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGLGSPLMGLTFINALVFGVQGNTLRALGHDSPLNQFLAGAAAGAIQCVICCPMELAKTRLQLQDAGPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPAGPALAQPSSL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Ubiquitination	LQVQSVEKPQYRGTL EEEEECCCCCCCCHH	34.95	29967540
48	Phosphorylation	GTLHCFKSIIKQESV CHHHHHHHHHHHHHH	14.86	24719451
66	Ubiquitination	YKGLGSPLMGLTFIN HCCCCCCCHHHHHHH	4.56	-
70	Phosphorylation	GSPLMGLTFINALVF CCCCHHHHHHHHHHH	19.42	26074081
132	Ubiquitination	AGPARTYKGSLDCLA CCCCCCCCCCHHHHH	41.22	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MCATL_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MCATL_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MCATL_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MCATL_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MCATL_HUMAN

Related Literatures of Post-Translational Modification