MBD2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MBD2_ARATH
• UniProt AC: Q8LA53
• Protein Name: Methyl-CpG-binding domain-containing protein 2
• Gene Name: MBD2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 272
• Subcellular Localization: Nucleus . Not present in chromocenters and the nucleolus.
• Protein Description: Probable transcriptional regulator..
• Protein Sequence: MSMSQSRAVQRSSSPNEDRGENQLVVYDLKGNDDTEEEVLPVQSQPLSSRTQCPSIGAFTVQCASCFKWRLMPSMQKYEEIREQLLENPFFCDTAREWKPDISCDVPADIYQDGTRLWAIDKPNISRPPAGWQRLLRIRGEGGTRFADVYYVAPSGKKLRSTVEVQKYLNDNSEYIGEGVKLSQFSFQIPKPLQDDYVRKRPARLLDSIDNTNTPVAKEANPLAWISPDDHISLQLGTPTESGLNNSHYQPSKKKKTSTLSIFGSNDELADR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	QSRAVQRSSSPNEDR HHHCCCCCCCCCCCC	20.34	23776212
13	Phosphorylation	SRAVQRSSSPNEDRG HHCCCCCCCCCCCCC	52.59	23776212
14	Phosphorylation	RAVQRSSSPNEDRGE HCCCCCCCCCCCCCC	32.75	24601666
27	Phosphorylation	GENQLVVYDLKGNDD CCCEEEEEECCCCCC	14.21	23776212
35	Phosphorylation	DLKGNDDTEEEVLPV ECCCCCCCCCCEECC	48.43	29654922
265	Phosphorylation	STLSIFGSNDELADR CEEECCCCCHHHCCC	30.29	30407730

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MBD2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MBD2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MBD2_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DDM1_ARATH	CHR1	physical	15805479

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.