MAST4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAST4_HUMAN
• UniProt AC: O15021
• Protein Name: Microtubule-associated serine/threonine-protein kinase 4 {ECO:0000305}
• Gene Name: MAST4 {ECO:0000312|HGNC:HGNC:19037}
• Organism: Homo sapiens (Human).
• Sequence Length: 2623
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MGEKVSEAPEPVPRGCSGHGSRTPASALVAASSPGASSAESSSGSETLSEEGEPGGFSREHQPPPPPPLGGTLGARAPAAWAPASVLLERGVLALPPPLPGGAVPPAPRGSSASQEEQDEELDHILSPPPMPFRKCSNPDVASGPGKSLKYKRQLSEDGRQLRRGSLGGALTGRYLLPNPVAGQAWPASAETSNLVRMRSQALGQSAPSLTASLKELSLPRRGSFCRTSNRKSLIGNGQSPALPRPHSPLSAHAGNSPQDSPRNFSPSASAHFSFARRTDGRRWSLASLPSSGYGTNTPSSTVSSSCSSQEKLHQLPYQPTPDELHFLSKHFCTTESIATENRCRNTPMRPRSRSLSPGRSPACCDHEIIMMNHVYKERFPKATAQMEERLKEIITSYSPDNVLPLADGVLSFTHHQIIELARDCLDKSHQGLITSRYFLELQHKLDKLLQEAHDRSESGELAFIKQLVRKILIVIARPARLLECLEFDPEEFYYLLEAAEGHAKEGQGIKTDIPRYIISQLGLNKDPLEEMAHLGNYDSGTAETPETDESVSSSNASLKLRRKPRESDFETIKLISNGAYGAVYFVRHKESRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATLMKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVGLMSMTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQDLITLLLRQNPLERLGTGGAYEVKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHRFSKVFSSIDRITQNSAEEKEDSVDKTKSTTLPSTETLSWSSEYSEMQQLSTSNSSDTESNRHKLSSGLLPKLAISTEGEQDEAASCPGDPHEEPGKPALPPEECAQEEPEVTTPASTISSSTLSVGSFSEHLDQINGRSECVDSTDNSSKPSSEPASHMARQRLESTEKKKISGKVTKSLSASALSLMIPGDMFAVSPLGSPMSPHSLSSDPSSSRDSSPSRDSSAASASPHQPIVIHSSGKNYGFTIRAIRVYVGDSDIYTVHHIVWNVEEGSPACQAGLKAGDLITHINGEPVHGLVHTEVIELLLKSGNKVSITTTPFENTSIKTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSSGESLPGSPTHSLSPRSPTPSYRSTPDFPSGTNSSQSSSPSSSAPNSPAGSGHIRPSTLHGLAPKLGGQRYRSGRRKSAGNIPLSPLARTPSPTPQPTSPQRSPSPLLGHSLGNSKIAQAFPSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSYGSDKKHLCSRKHSLEVTQEEVQREQSQREAPLQSLDENVCDVPPLSRARPVEQGCLKRPVSRKVGRQESVDDLDRDKLKAKVVVKKADGFPEKQESHQKSHGPGSDLENFALFKLEEREKKVYPKAVERSSTFENKASMQEAPPLGSLLKDALHKQASVRASEGAMSDGRVPAEHRQGGGDFRRAPAPGTLQDGLCHSLDRGISGKGEGTEKSSQAKELLRCEKLDSKLANIDYLRKKMSLEDKEDNLCPVLKPKMTAGSHECLPGNPVRPTGGQQEPPPASESRAFVSSTHAAQMSAVSFVPLKALTGRVDSGTEKPGLVAPESPVRKSPSEYKLEGRSVSCLKPIEGTLDIALLSGPQASKTELPSPESAQSPSPSGDVRASVPPVLPSSSGKKNDTTSARELSPSSLKMNKSYLLEPWFLPPSRGLQNSPAVSLPDPEFKRDRKGPHPTARSPGTVMESNPQQREGSSPKHQDHTTDPKLLTCLGQNLHSPDLARPRCPLPPEASPSREKPGLRESSERGPPTARSERSAARADTCREPSMELCFPETAKTSDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGGKTNHKDGPGEARPPPRDNSSLHSAGIPCEKELGKVRRGVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKEQPLQRHPSSIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAKPSTAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGATKGKEPATQSLGGSSREGKGHSKSGPDVFPATPGSQNKASDGIGQGEGGPSVPLHTDRAPLDAKPQPTSGGRPLEVLEKPVHLPRPGHPGPSEPADQKLSAVGEKQTLSPKHPKPSTVKDCPTLCKQTDNRQTDKSPSQPAANTDRRAEGKKCTEALYAPAEGDKLEAGLSFVHSENRLKGAERPAAGVGKGFPEARGKGPGPQKPPTEADKPNGMKRSPSATGQSSFRSTALPEKSLSCSSSFPETRAGVREASAASSDTSSAKAAGGMLELPAPSNRDHRKAQPAGEGRTHMTKSDSLPSFRVSTLPLESHHPDPNTMGGASHRDRALSVTATVGETKGKDPAPAQPPPARKQNVGRDVTKPSPAPNTDRPISLSNEKDFVVRQRRGKESLRSSPHKKAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	CSGHGSRTPASALVA CCCCCCCCCHHHHHH	25.55	27251275
23 (in isoform 3)	Phosphorylation	-	25.55	22985185
32	Phosphorylation	ASALVAASSPGASSA HHHHHHHCCCCCCCC	27.59	-
72 (in isoform 2)	Phosphorylation	-	21.88	25849741
74 (in isoform 2)	Phosphorylation	-	16.92	23186163
76 (in isoform 2)	Phosphorylation	-	39.03	29743597
77 (in isoform 3)	Phosphorylation	-	9.50	25849741
79 (in isoform 3)	Phosphorylation	-	18.04	23186163
81 (in isoform 3)	Phosphorylation	-	12.60	29743597
84	Phosphorylation	APAAWAPASVLLERG CCCCCCCHHHHHHCC	12.43	30153514
86	Phosphorylation	AAWAPASVLLERGVL CCCCCHHHHHHCCCC	8.42	23186163
114	Phosphorylation	APRGSSASQEEQDEE CCCCCCCCHHHHHHH	39.82	17525332
137	Phosphorylation	PMPFRKCSNPDVASG CCCCCCCCCCCCCCC	55.20	25849741
156	Phosphorylation	LKYKRQLSEDGRQLR HHHHHHHCCCCCCCC	25.88	24719451
164	Methylation	EDGRQLRRGSLGGAL CCCCCCCCCCCCCCC	47.87	115482639
166	Phosphorylation	GRQLRRGSLGGALTG CCCCCCCCCCCCCCC	23.25	25849741
200	Phosphorylation	SNLVRMRSQALGQSA HHHHHHHHHHHCCCC	15.51	30242111
206	Phosphorylation	RSQALGQSAPSLTAS HHHHHCCCCHHHHHH	40.11	22617229
209	Phosphorylation	ALGQSAPSLTASLKE HHCCCCHHHHHHHHH	37.76	29978859
211	Phosphorylation	GQSAPSLTASLKELS CCCCHHHHHHHHHCC	20.66	29978859
213	Phosphorylation	SAPSLTASLKELSLP CCHHHHHHHHHCCCC	34.44	25849741
213	Phosphorylation	SAPSLTASLKELSLP CCHHHHHHHHHCCCC	34.44	25849741
218	Phosphorylation	TASLKELSLPRRGSF HHHHHHCCCCCCCCC	37.10	24719451
224 (in isoform 4)	Phosphorylation	-	23.60	22985185
233	Phosphorylation	CRTSNRKSLIGNGQS CCCCCCCCCCCCCCC	23.21	28348404
240	Phosphorylation	SLIGNGQSPALPRPH CCCCCCCCCCCCCCC	17.34	28348404
248	Phosphorylation	PALPRPHSPLSAHAG CCCCCCCCCCCCCCC	30.16	25849741
251	Phosphorylation	PRPHSPLSAHAGNSP CCCCCCCCCCCCCCC	22.76	23927012
257	Phosphorylation	LSAHAGNSPQDSPRN CCCCCCCCCCCCCCC	24.03	29743597
261	Phosphorylation	AGNSPQDSPRNFSPS CCCCCCCCCCCCCCC	22.10	27732954
266	Phosphorylation	QDSPRNFSPSASAHF CCCCCCCCCCCCCEE	22.84	25849741
266	Phosphorylation	QDSPRNFSPSASAHF CCCCCCCCCCCCCEE	22.84	27461979
268	Phosphorylation	SPRNFSPSASAHFSF CCCCCCCCCCCEEEE	33.39	23186163
268	Phosphorylation	SPRNFSPSASAHFSF CCCCCCCCCCCEEEE	33.39	23403867
270	Phosphorylation	RNFSPSASAHFSFAR CCCCCCCCCEEEEEE	26.98	29743597
270	Phosphorylation	RNFSPSASAHFSFAR CCCCCCCCCEEEEEE	26.98	23403867
274	Phosphorylation	PSASAHFSFARRTDG CCCCCEEEEEECCCC	14.23	27461979
285	Phosphorylation	RTDGRRWSLASLPSS CCCCCCEEEECCCCC	39.44	27251275
288	Phosphorylation	GRRWSLASLPSSGYG CCCEEEECCCCCCCC	16.55	23927012
291	Phosphorylation	WSLASLPSSGYGTNT EEEECCCCCCCCCCC	46.21	23403867
294	Phosphorylation	ASLPSSGYGTNTPSS ECCCCCCCCCCCCCC	41.51	23403867
295	Phosphorylation	SLPSSGYGTNTPSST CCCCCCCCCCCCCCC	33.81	23403867
297	Phosphorylation	PSSGYGTNTPSSTVS CCCCCCCCCCCCCCC	23.79	23403867
298	Phosphorylation	SSGYGTNTPSSTVSS CCCCCCCCCCCCCCC	18.93	-
299	Phosphorylation	SGYGTNTPSSTVSSS CCCCCCCCCCCCCCC	27.69	23403867
301	Phosphorylation	YGTNTPSSTVSSSCS CCCCCCCCCCCCCCC	25.12	23403867
303	Phosphorylation	TNTPSSTVSSSCSSQ CCCCCCCCCCCCCCC	36.28	23403867
304	Phosphorylation	NTPSSTVSSSCSSQE CCCCCCCCCCCCCCH	33.75	23403867
305	Phosphorylation	TPSSTVSSSCSSQEK CCCCCCCCCCCCCHH	28.83	23403867
307	Phosphorylation	SSTVSSSCSSQEKLH CCCCCCCCCCCHHHH	19.34	23403867
308	Phosphorylation	STVSSSCSSQEKLHQ CCCCCCCCCCHHHHC	30.90	23403867
309	Phosphorylation	TVSSSCSSQEKLHQL CCCCCCCCCHHHHCC	15.54	23403867
311	Phosphorylation	SSSCSSQEKLHQLPY CCCCCCCHHHHCCCC	36.68	23403867
312	Phosphorylation	SSCSSQEKLHQLPYQ CCCCCCHHHHCCCCC	46.84	23403867
324	Phosphorylation	PYQPTPDELHFLSKH CCCCCHHHHHHHHHH	28.04	25056879
353	Phosphorylation	NTPMRPRSRSLSPGR CCCCCCCCCCCCCCC	25.36	24719451
355	Phosphorylation	PMRPRSRSLSPGRSP CCCCCCCCCCCCCCC	34.05	27251275
356	Phosphorylation	MRPRSRSLSPGRSPA CCCCCCCCCCCCCCC	28.98	23663014
357	Phosphorylation	RPRSRSLSPGRSPAC CCCCCCCCCCCCCCC	42.78	24719451
358	Phosphorylation	PRSRSLSPGRSPACC CCCCCCCCCCCCCCC	34.15	22167270
360	Phosphorylation	SRSLSPGRSPACCDH CCCCCCCCCCCCCCC	26.93	22167270
364	Phosphorylation	SPGRSPACCDHEIIM CCCCCCCCCCCHHHC	23.82	27251275
438	Phosphorylation	QGLITSRYFLELQHK HHHHHHHHHHHHHHH	16.52	24719451
439	Phosphorylation	GLITSRYFLELQHKL HHHHHHHHHHHHHHH	20.28	30631047
460	Phosphorylation	AHDRSESGELAFIKQ HHHCCCCCHHHHHHH	42.02	25627689
462	Phosphorylation	DRSESGELAFIKQLV HCCCCCHHHHHHHHH	38.52	25627689
580	Phosphorylation	IKLISNGAYGAVYFV EEEHHHCCCCEEEEE	39.38	-
603	Ubiquitination	FAMKKINKQNLILRN HHHHHHCHHHHHHHH	38.13	-
659	Ubiquitination	GGDCATLMKNMGPLP CCHHHHHHHHCCCCC	14.44	-
686	Phosphorylation	LALEYLHNYGIVHRD HHHHHHHHCCCCCCC	17.70	22817900
690	Phosphorylation	YLHNYGIVHRDLKPD HHHHCCCCCCCCCCC	9.47	22817900
713	Phosphorylation	HIKLTDFGLSKVGLM CEEECCCCCCHHHHH	25.04	19369195
715	Phosphorylation	KLTDFGLSKVGLMSM EECCCCCCHHHHHHC	10.00	-
718	Phosphorylation	DFGLSKVGLMSMTTN CCCCCHHHHHHCCCC	26.19	19060867
726	Phosphorylation	LMSMTTNLYEGHIEK HHHCCCCCHHCCCHH	12.77	-
727	Phosphorylation	MSMTTNLYEGHIEKD HHCCCCCHHCCCHHH	18.00	-
730	Phosphorylation	TTNLYEGHIEKDARE CCCCHHCCCHHHHHH	23.18	-
741	Ubiquitination	DAREFLDKQVCGTPE HHHHHHHHHCCCCHH	9.97	-
828	Methylation	LRQNPLERLGTGGAY HHHCHHHHHCCCCCC	27.53	-
831	Methylation	NPLERLGTGGAYEVK CHHHHHCCCCCCHHH	46.21	-
838	Ubiquitination	TGGAYEVKQHRFFRS CCCCCHHHHHHHHHH	25.24	-
855	Ubiquitination	WNSLLRQKAEFIPQL HHHHHHHHHHHHHHC	5.67	-
864	Phosphorylation	EFIPQLESEDDTSYF HHHHHCCCCCCCCCC	53.71	27251275
867	Phosphorylation	PQLESEDDTSYFDTR HHCCCCCCCCCCCCC	55.72	26657352
871	Phosphorylation	SEDDTSYFDTRSEKY CCCCCCCCCCCCHHH	37.33	27251275
872	Phosphorylation	EDDTSYFDTRSEKYH CCCCCCCCCCCHHHC	30.69	27251275
873	Phosphorylation	DDTSYFDTRSEKYHH CCCCCCCCCCHHHCC	13.94	23403867
876	Phosphorylation	SYFDTRSEKYHHMET CCCCCCCHHHCCCCC	26.62	23403867
905	Phosphorylation	IRQFSSCSHRFSKVF HHHHHHCHHHHHHHH	23.30	22798277
906	Phosphorylation	RQFSSCSHRFSKVFS HHHHHCHHHHHHHHH	22.41	27251275
908	Phosphorylation	FSSCSHRFSKVFSSI HHHCHHHHHHHHHHH	21.46	22798277
912	Phosphorylation	SHRFSKVFSSIDRIT HHHHHHHHHHHHHHH	28.06	27251275
913	Phosphorylation	HRFSKVFSSIDRITQ HHHHHHHHHHHHHHC	44.58	27251275
914	Phosphorylation	RFSKVFSSIDRITQN HHHHHHHHHHHHHCC	5.65	24719451
916	Phosphorylation	SKVFSSIDRITQNSA HHHHHHHHHHHCCCH	29.39	22199227
917	Phosphorylation	KVFSSIDRITQNSAE HHHHHHHHHHCCCHH	19.62	25849741
922	Phosphorylation	IDRITQNSAEEKEDS HHHHHCCCHHHHHCC	23.69	22199227
925	Phosphorylation	ITQNSAEEKEDSVDK HHCCCHHHHHCCCCC	27.52	23090842
944	Phosphorylation	TLPSTETLSWSSEYS CCCCCCCCCCCHHHH	30.93	25954137
946	Phosphorylation	PSTETLSWSSEYSEM CCCCCCCCCHHHHHH	26.61	-
948	Phosphorylation	TETLSWSSEYSEMQQ CCCCCCCHHHHHHHH	32.12	-
951	Phosphorylation	LSWSSEYSEMQQLST CCCCHHHHHHHHHHC	34.00	25954137
962	Phosphorylation	QLSTSNSSDTESNRH HHHCCCCCCCHHHHH	31.19	-
964	Phosphorylation	STSNSSDTESNRHKL HCCCCCCCHHHHHHH	29.38	-
965	Phosphorylation	TSNSSDTESNRHKLS CCCCCCCHHHHHHHH	53.45	25954137
967	Phosphorylation	NSSDTESNRHKLSSG CCCCCHHHHHHHHCC	43.17	25954137
969	Phosphorylation	SDTESNRHKLSSGLL CCCHHHHHHHHCCHH	41.05	25954137
972	Phosphorylation	ESNRHKLSSGLLPKL HHHHHHHHCCHHCCE	39.39	27251275
973	Phosphorylation	SNRHKLSSGLLPKLA HHHHHHHCCHHCCEE	46.99	20068231
975	Phosphorylation	RHKLSSGLLPKLAIS HHHHHCCHHCCEEEC	27.45	23403867
976	Phosphorylation	HKLSSGLLPKLAIST HHHHCCHHCCEEECC	43.85	23403867
1087	Phosphorylation	SGKVTKSLSASALSL CCCHHHHCCHHHHHH	20.57	29449344
1091	Phosphorylation	TKSLSASALSLMIPG HHHCCHHHHHHHCCC	27.54	30624053
1093	Phosphorylation	SLSASALSLMIPGDM HCCHHHHHHHCCCCC	26.77	30624053
1096	Phosphorylation	ASALSLMIPGDMFAV HHHHHHHCCCCCEEE	18.66	30624053
1107	Phosphorylation	MFAVSPLGSPMSPHS CEEEECCCCCCCCCC	15.81	30624053
1111	Phosphorylation	SPLGSPMSPHSLSSD ECCCCCCCCCCCCCC	25.72	30624053
1114	Phosphorylation	GSPMSPHSLSSDPSS CCCCCCCCCCCCCCC	23.89	30624053
1117	Phosphorylation	MSPHSLSSDPSSSRD CCCCCCCCCCCCCCC	33.07	30624053
1119	Phosphorylation	PHSLSSDPSSSRDSS CCCCCCCCCCCCCCC	35.39	30624053
1120	Phosphorylation	HSLSSDPSSSRDSSP CCCCCCCCCCCCCCC	59.85	30624053
1123	Phosphorylation	SSDPSSSRDSSPSRD CCCCCCCCCCCCCCC	46.03	30624053
1124	Phosphorylation	SDPSSSRDSSPSRDS CCCCCCCCCCCCCCC	34.48	30624053
1125	Phosphorylation	DPSSSRDSSPSRDSS CCCCCCCCCCCCCCC	44.43	30624053
1126	Phosphorylation	PSSSRDSSPSRDSSA CCCCCCCCCCCCCCC	50.18	27251275
1128	Phosphorylation	SSRDSSPSRDSSAAS CCCCCCCCCCCCCCC	42.93	28270605
1129	Phosphorylation	SRDSSPSRDSSAASA CCCCCCCCCCCCCCC	31.05	28857561
1131	Phosphorylation	DSSPSRDSSAASASP CCCCCCCCCCCCCCC	51.14	27251275
1134	Phosphorylation	PSRDSSAASASPHQP CCCCCCCCCCCCCCC	22.29	28857561
1135	Phosphorylation	SRDSSAASASPHQPI CCCCCCCCCCCCCCE	31.95	28270605
1138	Phosphorylation	SSAASASPHQPIVIH CCCCCCCCCCCEEEE	29.06	28270605
1140	Phosphorylation	AASASPHQPIVIHSS CCCCCCCCCEEEEEC	22.03	28270605
1149	Phosphorylation	IVIHSSGKNYGFTIR EEEEECCCCCEEEEE	29.66	23312004
1150	Phosphorylation	VIHSSGKNYGFTIRA EEEECCCCCEEEEEE	39.36	23312004
1157	Phosphorylation	NYGFTIRAIRVYVGD CCEEEEEEEEEEECC	12.75	24719451
1238	Phosphorylation	TSIKTGPARRNSYKS CCCCCCCCCHHHHHH	46.88	25332170
1245	Phosphorylation	ARRNSYKSRMVRRSK CCHHHHHHHHHHHCH	31.93	-
1248	Phosphorylation	NSYKSRMVRRSKKSK HHHHHHHHHHCHHHH	19.85	-
1257	Phosphorylation	RSKKSKKKESLERRR HCHHHHHHHHHHHHH	54.14	26657352
1262	Phosphorylation	KKKESLERRRSLFKK HHHHHHHHHHHHHHH	44.39	26657352
1265	Phosphorylation	ESLERRRSLFKKLAK HHHHHHHHHHHHHHC	44.60	24719451
1268	Phosphorylation	ERRRSLFKKLAKQPS HHHHHHHHHHHCCCC	36.02	24719451
1275	Phosphorylation	KKLAKQPSPLLHTSR HHHHCCCCCCCCCCC	73.51	24719451
1278	Phosphorylation	AKQPSPLLHTSRSFS HCCCCCCCCCCCCCH	26.20	26657352
1283	Phosphorylation	PLLHTSRSFSCLNRS CCCCCCCCCHHHHCC	26.29	24719451
1284	Phosphorylation	LLHTSRSFSCLNRSL CCCCCCCCHHHHCCC	18.38	23403867
1286	Phosphorylation	HTSRSFSCLNRSLSS CCCCCCHHHHCCCCC	22.68	23401153
1288	Phosphorylation	SRSFSCLNRSLSSGE CCCCHHHHCCCCCCC	20.95	28857561
1290	Phosphorylation	SFSCLNRSLSSGESL CCHHHHCCCCCCCCC	6.05	-
1292	Phosphorylation	SCLNRSLSSGESLPG HHHHCCCCCCCCCCC	26.48	24719451
1293	Phosphorylation	CLNRSLSSGESLPGS HHHCCCCCCCCCCCC	31.37	23403867
1295	Phosphorylation	NRSLSSGESLPGSPT HCCCCCCCCCCCCCC	37.23	23401153
1296	Phosphorylation	RSLSSGESLPGSPTH CCCCCCCCCCCCCCC	52.45	23403867
1299	Phosphorylation	SSGESLPGSPTHSLS CCCCCCCCCCCCCCC	43.31	23403867
1300	Phosphorylation	SGESLPGSPTHSLSP CCCCCCCCCCCCCCC	4.91	-
1303	Phosphorylation	SLPGSPTHSLSPRSP CCCCCCCCCCCCCCC	25.37	23403867
1305	Phosphorylation	PGSPTHSLSPRSPTP CCCCCCCCCCCCCCC	26.29	23403867
1307	Phosphorylation	SPTHSLSPRSPTPSY CCCCCCCCCCCCCCC	32.78	23403867
1309	Phosphorylation	THSLSPRSPTPSYRS CCCCCCCCCCCCCCC	22.68	23403867
1312	Phosphorylation	LSPRSPTPSYRSTPD CCCCCCCCCCCCCCC	36.19	23403867
1314	Phosphorylation	PRSPTPSYRSTPDFP CCCCCCCCCCCCCCC	26.55	23403867
1316	Phosphorylation	SPTPSYRSTPDFPSG CCCCCCCCCCCCCCC	35.34	23403867
1317	Phosphorylation	PTPSYRSTPDFPSGT CCCCCCCCCCCCCCC	15.13	23403867
1336	Phosphorylation	SSSPSSSAPNSPAGS CCCCCCCCCCCCCCC	38.58	22798277
1370	Phosphorylation	YRSGRRKSAGNIPLS CCCCCCCCCCCCCCC	44.06	24719451
1373	Phosphorylation	GRRKSAGNIPLSPLA CCCCCCCCCCCCCCC	39.33	23401153
1377	Phosphorylation	SAGNIPLSPLARTPS CCCCCCCCCCCCCCC	3.39	24719451
1380	Phosphorylation	NIPLSPLARTPSPTP CCCCCCCCCCCCCCC	16.71	23927012
1382	Phosphorylation	PLSPLARTPSPTPQP CCCCCCCCCCCCCCC	4.53	-
1384	Phosphorylation	SPLARTPSPTPQPTS CCCCCCCCCCCCCCC	55.65	24719451
1385	Phosphorylation	PLARTPSPTPQPTSP CCCCCCCCCCCCCCC	23.63	23403867
1386	Phosphorylation	LARTPSPTPQPTSPQ CCCCCCCCCCCCCCC	32.53	-
1387	Phosphorylation	ARTPSPTPQPTSPQR CCCCCCCCCCCCCCC	40.57	23927012
1389	Phosphorylation	TPSPTPQPTSPQRSP CCCCCCCCCCCCCCC	38.60	23403867
1390	Phosphorylation	PSPTPQPTSPQRSPS CCCCCCCCCCCCCCC	41.35	24719451
1391	Phosphorylation	SPTPQPTSPQRSPSP CCCCCCCCCCCCCCC	57.28	27251275
1393	Phosphorylation	TPQPTSPQRSPSPLL CCCCCCCCCCCCCCC	48.03	23927012
1394	Phosphorylation	PQPTSPQRSPSPLLG CCCCCCCCCCCCCCC	26.22	25849741
1395	Phosphorylation	QPTSPQRSPSPLLGH CCCCCCCCCCCCCCC	35.76	27251275
1397	Phosphorylation	TSPQRSPSPLLGHSL CCCCCCCCCCCCCCC	54.65	24719451
1398	Phosphorylation	SPQRSPSPLLGHSLG CCCCCCCCCCCCCCC	25.20	23403867
1400	Phosphorylation	QRSPSPLLGHSLGNS CCCCCCCCCCCCCCC	29.44	23927012
1406	Phosphorylation	LLGHSLGNSKIAQAF CCCCCCCCCHHHHHC	35.85	23403867
1410	Phosphorylation	SLGNSKIAQAFPSKM CCCCCHHHHHCCCCC	24.52	23403867
1418	Phosphorylation	QAFPSKMHSPPTIVR HHCCCCCCCCCEEEH	35.84	-
1419	Phosphorylation	AFPSKMHSPPTIVRH HCCCCCCCCCEEEHH	40.65	23186163
1422	Phosphorylation	SKMHSPPTIVRHIVR CCCCCCCEEEHHCCC	29.13	23401153
1425	Phosphorylation	HSPPTIVRHIVRPKS CCCCEEEHHCCCCCC	35.17	23403867
1432	Phosphorylation	RHIVRPKSAEPPRSP HHCCCCCCCCCCCCH	32.12	27251275
1435	Phosphorylation	VRPKSAEPPRSPLLK CCCCCCCCCCCHHHH	40.31	30266825
1438	Phosphorylation	KSAEPPRSPLLKRVQ CCCCCCCCHHHHHHC	29.35	27251275
1441	Phosphorylation	EPPRSPLLKRVQSEE CCCCCHHHHHHCCCC	26.18	23401153
1442	Methylation	PPRSPLLKRVQSEEK CCCCHHHHHHCCCCC	42.88	-
1445	Methylation	SPLLKRVQSEEKLSP CHHHHHHCCCCCCCC	59.20	-
1446	Phosphorylation	PLLKRVQSEEKLSPS HHHHHHCCCCCCCCC	31.51	-
1449	Phosphorylation	KRVQSEEKLSPSYGS HHHCCCCCCCCCCCC	44.88	25849741
1454	Phosphorylation	EEKLSPSYGSDKKHL CCCCCCCCCCCHHHH	23.91	23312004
1456	Phosphorylation	KLSPSYGSDKKHLCS CCCCCCCCCHHHHHH	38.46	29759185
1459	Phosphorylation	PSYGSDKKHLCSRKH CCCCCCHHHHHHCHH	37.71	29759185
1467	Phosphorylation	HLCSRKHSLEVTQEE HHHHCHHHHCCCHHH	39.44	24719451
1470	Phosphorylation	SRKHSLEVTQEEVQR HCHHHHCCCHHHHHH	29.30	23401153
1474	Phosphorylation	SLEVTQEEVQREQSQ HHCCCHHHHHHHHHH	22.38	23403867
1523	Phosphorylation	RKVGRQESVDDLDRD CCCCCCCCCCCCCHH	39.83	24719451
1526	Phosphorylation	GRQESVDDLDRDKLK CCCCCCCCCCHHHHH	23.62	23401153
1587	Phosphorylation	AVERSSTFENKASMQ HHHCCCCCCCHHHHH	21.89	26437602
1589	Phosphorylation	ERSSTFENKASMQEA HCCCCCCCHHHHHHC	35.89	25849741
1595	Phosphorylation	ENKASMQEAPPLGSL CCHHHHHHCCCHHHH	23.70	-
1604	Phosphorylation	PPLGSLLKDALHKQA CCHHHHHHHHHHHHH	37.91	24719451
1640	Methylation	GGDFRRAPAPGTLQD CCCCCCCCCCCCCCC	38.29	-
1641	Methylation	GDFRRAPAPGTLQDG CCCCCCCCCCCCCCC	44.94	-
1652	Phosphorylation	LQDGLCHSLDRGISG CCCCCHHHCCCCCCC	2.98	27251275
1655	Phosphorylation	GLCHSLDRGISGKGE CCHHHCCCCCCCCCC	30.85	28348404
1694	Phosphorylation	DYLRKKMSLEDKEDN HHHHHHCCCCCCCCC	50.67	24719451
1697	Phosphorylation	RKKMSLEDKEDNLCP HHHCCCCCCCCCCCC	37.17	25849741
1772	Phosphorylation	VDSGTEKPGLVAPES CCCCCCCCCCCCCCC	44.80	23403867
1779	Phosphorylation	PGLVAPESPVRKSPS CCCCCCCCCCCCCCC	13.74	24719451
1782	Phosphorylation	VAPESPVRKSPSEYK CCCCCCCCCCCCCCC	27.86	30266825
1789	Phosphorylation	RKSPSEYKLEGRSVS CCCCCCCCCCCCEEC	61.73	30387612
1791	Phosphorylation	SPSEYKLEGRSVSCL CCCCCCCCCCEECCC	25.80	30387612
1821	Phosphorylation	QASKTELPSPESAQS CCCCCCCCCCHHCCC	40.01	30266825
1822	Phosphorylation	ASKTELPSPESAQSP CCCCCCCCCHHCCCC	63.52	24719451
1825	Phosphorylation	TELPSPESAQSPSPS CCCCCCHHCCCCCCC	54.66	30266825
1828	Phosphorylation	PSPESAQSPSPSGDV CCCHHCCCCCCCCCC	34.68	25849741
1831	Phosphorylation	ESAQSPSPSGDVRAS HHCCCCCCCCCCCCC	27.36	30266825
1833	Phosphorylation	AQSPSPSGDVRASVP CCCCCCCCCCCCCCC	36.62	23403867
1835	Phosphorylation	SPSPSGDVRASVPPV CCCCCCCCCCCCCCC	52.54	23186163
1841	Phosphorylation	DVRASVPPVLPSSSG CCCCCCCCCCCCCCC	25.29	-
1845	Phosphorylation	SVPPVLPSSSGKKND CCCCCCCCCCCCCCC	11.40	-
1847	Phosphorylation	PPVLPSSSGKKNDTT CCCCCCCCCCCCCCC	32.19	-
1848	Phosphorylation	PVLPSSSGKKNDTTS CCCCCCCCCCCCCCC	32.73	21712546
1849	Phosphorylation	VLPSSSGKKNDTTSA CCCCCCCCCCCCCCH	40.96	-
1850	Phosphorylation	LPSSSGKKNDTTSAR CCCCCCCCCCCCCHH	59.99	21712546
1855	Phosphorylation	GKKNDTTSARELSPS CCCCCCCCHHHCCHH	61.31	-
1858	Phosphorylation	NDTTSARELSPSSLK CCCCCHHHCCHHHHC	27.67	-
1860	Phosphorylation	TTSARELSPSSLKMN CCCHHHCCHHHHCCC	45.19	24719451
1863	Phosphorylation	ARELSPSSLKMNKSY HHHCCHHHHCCCHHH	20.27	25849741
1865	Methylation	ELSPSSLKMNKSYLL HCCHHHHCCCHHHHC	44.95	-
1865	Phosphorylation	ELSPSSLKMNKSYLL HCCHHHHCCCHHHHC	44.95	23403867
1866	Phosphorylation	LSPSSLKMNKSYLLE CCHHHHCCCHHHHCC	35.08	25849741
1868	Methylation	PSSLKMNKSYLLEPW HHHHCCCHHHHCCCC	42.23	115972811
1871	Methylation	LKMNKSYLLEPWFLP HCCCHHHHCCCCCCC	36.66	-
1906	Phosphorylation	DRKGPHPTARSPGTV CCCCCCCCCCCCCCC	33.06	20068231
1909	Phosphorylation	GPHPTARSPGTVMES CCCCCCCCCCCCCCC	31.50	20068231
1912	Phosphorylation	PTARSPGTVMESNPQ CCCCCCCCCCCCCCC	25.80	20068231
1915	Phosphorylation	RSPGTVMESNPQQRE CCCCCCCCCCCCCCC	21.77	17924679
1916	Phosphorylation	SPGTVMESNPQQREG CCCCCCCCCCCCCCC	5.06	17924679
1917	Sulfoxidation	PGTVMESNPQQREGS CCCCCCCCCCCCCCC	4.73	21406390
1919	Phosphorylation	TVMESNPQQREGSSP CCCCCCCCCCCCCCC	35.40	17924679
1942	Phosphorylation	PKLLTCLGQNLHSPD HHHHHHHCCCCCCCC	19.00	23403867
1947	Phosphorylation	CLGQNLHSPDLARPR HHCCCCCCCCCCCCC	37.61	24719451
1950	Phosphorylation	QNLHSPDLARPRCPL CCCCCCCCCCCCCCC	24.23	23927012
1965	Phosphorylation	PPEASPSREKPGLRE CCCCCCCCCCCCCCC	23.03	26699800
1967	Phosphorylation	EASPSREKPGLRESS CCCCCCCCCCCCCCC	51.05	26329039
1995	Phosphorylation	ARADTCREPSMELCF HHCCCCCCCCCHHHC	16.69	28348404
2000	Phosphorylation	CREPSMELCFPETAK CCCCCCHHHCCCCCC	21.82	28348404
2020	Phosphorylation	KNLLSVGRTHPDFYT CCCHHCCCCCCCHHH	26.20	29978859
2024	Phosphorylation	SVGRTHPDFYTQTQA HCCCCCCCHHHHHHH	31.65	29978859
2029	Phosphorylation	HPDFYTQTQAMEKAW CCCHHHHHHHHHHHC	12.81	29978859
2030	Phosphorylation	PDFYTQTQAMEKAWA CCHHHHHHHHHHHCC	25.74	29978859
2032	Phosphorylation	FYTQTQAMEKAWAPG HHHHHHHHHHHCCCC	15.53	28787133
2091	Phosphorylation	EALLARRSLQPPGIE HHHHHHHCCCCCCCC	12.99	27251275
2094	Phosphorylation	LARRSLQPPGIESEK HHHHCCCCCCCCCHH	26.29	27251275
2131	Phosphorylation	QPLQRHPSSIPPPPL CCCHHCCCCCCCCCC	51.90	27251275
2134	Phosphorylation	QRHPSSIPPPPLTAK HHCCCCCCCCCCCHH	34.47	28857561
2135	Phosphorylation	RHPSSIPPPPLTAKD HCCCCCCCCCCCHHH	43.49	27251275
2213	Phosphorylation	KHPDRSLSSQKPSVG CCCCCCCCCCCCCCC	43.90	24719451
2214	Phosphorylation	HPDRSLSSQKPSVGA CCCCCCCCCCCCCCC	39.73	25954137
2216	Phosphorylation	DRSLSSQKPSVGATK CCCCCCCCCCCCCCC	31.78	24719451
2217	Phosphorylation	RSLSSQKPSVGATKG CCCCCCCCCCCCCCC	47.74	25954137
2234	Phosphorylation	PATQSLGGSSREGKG CCCCCCCCCCCCCCC	25.32	-
2238	Phosphorylation	SLGGSSREGKGHSKS CCCCCCCCCCCCCCC	25.15	-
2245	Phosphorylation	EGKGHSKSGPDVFPA CCCCCCCCCCCCCCC	35.22	27251275
2246	Phosphorylation	GKGHSKSGPDVFPAT CCCCCCCCCCCCCCC	36.87	-
2248	Phosphorylation	GHSKSGPDVFPATPG CCCCCCCCCCCCCCC	59.58	27251275
2330	Phosphorylation	VGEKQTLSPKHPKPS HCCCCCCCCCCCCCC	43.29	24719451
2333	Phosphorylation	KQTLSPKHPKPSTVK CCCCCCCCCCCCCCC	34.98	24719451
2357	Phosphorylation	DNRQTDKSPSQPAAN CCCCCCCCCCCCCCC	42.00	23898821
2360	Phosphorylation	QTDKSPSQPAANTDR CCCCCCCCCCCCCCC	32.37	21130716
2382	Phosphorylation	TEALYAPAEGDKLEA HHHHCCCCCCCCCHH	20.00	-
2395	Phosphorylation	EAGLSFVHSENRLKG HHCCEEECCCCCCCC	25.06	-
2399	Phosphorylation	SFVHSENRLKGAERP EEECCCCCCCCCCCC	31.12	-
2440	Phosphorylation	KPNGMKRSPSATGQS CCCCCCCCCCCCCCC	4.07	27251275
2442	Phosphorylation	NGMKRSPSATGQSSF CCCCCCCCCCCCCCC	44.93	24719451
2443	Phosphorylation	GMKRSPSATGQSSFR CCCCCCCCCCCCCCC	20.07	25159151
2445	Phosphorylation	KRSPSATGQSSFRST CCCCCCCCCCCCCCC	39.44	23927012
2447	Phosphorylation	SPSATGQSSFRSTAL CCCCCCCCCCCCCCC	39.84	23403867
2450	Phosphorylation	ATGQSSFRSTALPEK CCCCCCCCCCCCCCC	32.56	23403867
2451	Phosphorylation	TGQSSFRSTALPEKS CCCCCCCCCCCCCCC	19.45	23403867
2460	Phosphorylation	ALPEKSLSCSSSFPE CCCCCCCCCCCCCHH	55.55	27251275
2461	Phosphorylation	LPEKSLSCSSSFPET CCCCCCCCCCCCHHH	24.69	23403867
2463	Phosphorylation	EKSLSCSSSFPETRA CCCCCCCCCCHHHHH	21.02	23403867
2465	Phosphorylation	SLSCSSSFPETRAGV CCCCCCCCHHHHHHH	26.16	23403867
2466	Phosphorylation	LSCSSSFPETRAGVR CCCCCCCHHHHHHHH	40.08	23403867
2479	Phosphorylation	VREASAASSDTSSAK HHHHHHCCCCCCCCH	21.44	23401153
2482	Phosphorylation	ASAASSDTSSAKAAG HHHCCCCCCCCHHHC	28.59	23401153
2483	Phosphorylation	SAASSDTSSAKAAGG HHCCCCCCCCHHHCC	39.93	23401153
2485	Phosphorylation	ASSDTSSAKAAGGML CCCCCCCCHHHCCCE	26.91	23401153
2486	Phosphorylation	SSDTSSAKAAGGMLE CCCCCCCHHHCCCEE	33.03	23401153
2487	Phosphorylation	SDTSSAKAAGGMLEL CCCCCCHHHCCCEEC	35.56	23401153
2520	Phosphorylation	THMTKSDSLPSFRVS CCCCCCCCCCCCEEE	44.70	20058876
2521	Phosphorylation	HMTKSDSLPSFRVST CCCCCCCCCCCEEEE	24.22	26657352
2523	Phosphorylation	TKSDSLPSFRVSTLP CCCCCCCCCEEEECC	49.63	23401153
2526	Phosphorylation	DSLPSFRVSTLPLES CCCCCCEEEECCCCC	30.86	29691806
2552	Phosphorylation	SHRDRALSVTATVGE CHHHCEEEEEEEECC	37.07	24719451
2555	Phosphorylation	DRALSVTATVGETKG HCEEEEEEEECCCCC	19.21	29255136
2557	Phosphorylation	ALSVTATVGETKGKD EEEEEEEECCCCCCC	17.15	29255136
2559	Phosphorylation	SVTATVGETKGKDPA EEEEEECCCCCCCCC	21.48	29255136
2563	Phosphorylation	TVGETKGKDPAPAQP EECCCCCCCCCCCCC	38.89	29255136
2586	Phosphorylation	GRDVTKPSPAPNTDR CCCCCCCCCCCCCCC	41.34	23312004
2589	Phosphorylation	VTKPSPAPNTDRPIS CCCCCCCCCCCCCCC	34.94	29507054
2594	Phosphorylation	PAPNTDRPISLSNEK CCCCCCCCCCCCCCC	32.12	29507054
2599	Phosphorylation	DRPISLSNEKDFVVR CCCCCCCCCCCEEEE	28.55	29507054
2601	Phosphorylation	PISLSNEKDFVVRQR CCCCCCCCCEEEEEC	35.83	23312004
2616	Phosphorylation	RGKESLRSSPHKKAL CCHHHHHCCCCCCCC	32.35	-
2619	Phosphorylation	ESLRSSPHKKAL--- HHHHCCCCCCCC---	54.22	28348404
2620	Phosphorylation	SLRSSPHKKAL---- HHHCCCCCCCC----	25.29	28348404

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAST4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAST4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAST4_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of MAST4_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions.";
Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.;
Sci. Signal. 2:RA46-RA46(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2555, AND MASSSPECTROMETRY.
PubMed: 19690332

"Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column.";
Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.;
Anal. Sci. 24:161-166(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1422, AND MASSSPECTROMETRY.
PubMed: 18187866

"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage.";
Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.;
Science 316:1160-1166(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-114, AND MASSSPECTROMETRY.
PubMed: 17525332

"Improved titanium dioxide enrichment of phosphopeptides from HeLacells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.";
Yu L.-R., Zhu Z., Chan K.C., Issaq H.J., Dimitrov D.S., Veenstra T.D.;
J. Proteome Res. 6:4150-4162(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1915 AND SER-1919, ANDMASS SPECTROMETRY.
PubMed: 17924679