MARE2_RAT - dbPTM
MARE2_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MARE2_RAT
UniProt AC Q3B8Q0
Protein Name Microtubule-associated protein RP/EB family member 2
Gene Name Mapre2
Organism Rattus norvegicus (Rat).
Sequence Length 326
Subcellular Localization Cytoplasm. Cytoplasm, cytoskeleton. Associated with the microtubule network. Accumulates at the plus end of microtubules (By similarity)..
Protein Description May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity)..
Protein Sequence MPGPTQTLSPNGENNNDIIQDNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHDIIAWVNDIVSLNYTKVEQLCSGAAYCQFMDMLFPGCISLKKVKFQAKLEHEYIHNFKLLQASFKRMNVDKVIPVEKLVKGRFQDNLDFIQWFKKFYDANYDGKEYDPVEARQGQDAIPPPDPGEQIFNLPKKSHHANSPTAGAAKSSPAAKPGSTPSRPSSAKRASSSGSASRSDKDLETQVIQLNEQVHSLKLALEGVEKERDFYFGKLREIELLCQEHGQENDDLVQRLMEVLYASDEQEGQTEEPEVEEQTHDQQPQQQEEY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Phosphorylation---MPGPTQTLSPNG
---CCCCCCCCCCCC		39.8527097102
7Phosphorylation-MPGPTQTLSPNGEN
-CCCCCCCCCCCCCC		31.5127097102
9PhosphorylationPGPTQTLSPNGENNN
CCCCCCCCCCCCCCC		21.5127097102
104AcetylationCISLKKVKFQAKLEH
CEEECEEEEEEECCC		40.4122902405
108AcetylationKKVKFQAKLEHEYIH
CEEEEEEECCCHHHH		43.5622902405
113PhosphorylationQAKLEHEYIHNFKLL
EEECCCHHHHHHHHH		14.91-
155UbiquitinationDFIQWFKKFYDANYD
HHHHHHHHHHCCCCC		39.42-
157PhosphorylationIQWFKKFYDANYDGK
HHHHHHHHCCCCCCC		24.03-
161PhosphorylationKKFYDANYDGKEYDP
HHHHCCCCCCCCCCC		28.00-
164UbiquitinationYDANYDGKEYDPVEA
HCCCCCCCCCCCCHH		50.64-
166PhosphorylationANYDGKEYDPVEARQ
CCCCCCCCCCCHHCC		29.09-
194PhosphorylationIFNLPKKSHHANSPT
HCCCCCCCCCCCCCC		26.9922673903
199PhosphorylationKKSHHANSPTAGAAK
CCCCCCCCCCCCCCC		25.1429779826
201PhosphorylationSHHANSPTAGAAKSS
CCCCCCCCCCCCCCC		37.2327097102
208PhosphorylationTAGAAKSSPAAKPGS
CCCCCCCCCCCCCCC		20.1828689409
215PhosphorylationSPAAKPGSTPSRPSS
CCCCCCCCCCCCCCC		45.7528432305
216PhosphorylationPAAKPGSTPSRPSSA
CCCCCCCCCCCCCCC		31.0627097102
218PhosphorylationAKPGSTPSRPSSAKR
CCCCCCCCCCCCCCC		57.8427097102
221PhosphorylationGSTPSRPSSAKRASS
CCCCCCCCCCCCCCC		41.6427097102
222PhosphorylationSTPSRPSSAKRASSS
CCCCCCCCCCCCCCC		40.2627097102
227PhosphorylationPSSAKRASSSGSASR
CCCCCCCCCCCCCCC		29.1228551015
228PhosphorylationSSAKRASSSGSASRS
CCCCCCCCCCCCCCC		37.4228551015
229PhosphorylationSAKRASSSGSASRSD
CCCCCCCCCCCCCCC		33.9828551015
231PhosphorylationKRASSSGSASRSDKD
CCCCCCCCCCCCCCH		25.6428551015
237AcetylationGSASRSDKDLETQVI
CCCCCCCCHHHHHHH		66.5122902405
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MARE2_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MARE2_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MARE2_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MARE2_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MARE2_RAT

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Related Literatures of Post-Translational Modification

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