MAP6_RAT - dbPTM
MAP6_RAT - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MAP6_RAT
UniProt AC Q63560
Protein Name Microtubule-associated protein 6
Gene Name Map6
Organism Rattus norvegicus (Rat).
Sequence Length 952
Subcellular Localization Cytoplasm, cytoskeleton . Golgi apparatus . Cell projection, axon . Cell projection, dendrite . Cytoplasmic vesicle, secretory vesicle membrane
Lipid-anchor
Cytoplasmic side . Isoform 1 and isoform 2 associate with axonal microtubules in neuronal
Protein Description Involved in microtubule stabilization in many cell types, including neuronal cells. [PubMed: 8700896]
Protein Sequence MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPAPPQPGLAPPSRAVAIETQPAQGESDAVARATGPAPGPSGDRETAAAPGRSGLGLGAASGSTSGSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQIPATSQPSPPVLGMPKRRPQSQERGPIQLSADARDPEGAGGAGVPAAGKASGADQRDTRRKAGPAWMVTRTEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADERDTRRKAGPAWMVRRSEGHEQTTAAHAQGTGPEGGKGRAVADALNRQIREEVTSTVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPDDKMVHETSYSAQFKGEASKPTTADNKVVDRRRIRSLYSEPFKESPKVEKPSVQSSKPKKTSTSQKPLRKAKDKQVASGQAAKKKTTESPSATKPDDKEQSKEMNNKLAEAKESRVKPTSDKNQGPVAKEPHKDQGPVAPGLPKGQGPAVQEPLKDQGPMVPGLPKDQAPVVPGSLKGQSPTAPGPPKDQGAVLLGPMKDLGPVAPASVKDQDHMASELLKNKDSVPLAPAKAQSPLLPEPLKNQSPVVPARAKDQSFPAPAPTPLKDPGPVIPEPEKDGAPMVPERRKDQNASIMASLKNEAPVASESVKNQGLGGPEPAKDTGTDLKGHGSVFVAPVKSQGPVVPEPTKGQDPIIPALAKDQGPILPEPPKNQGPPVVLGPIKNQDPVIPVPLKGQDPVVPAPTKDPGPTAPDPLKSQGPRGPQLPTVSPSPPVMIPTVPHAEYIEGSP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5S-palmitoylation---MAWPCITRACCI
---CCCHHHHHHHHH		3.2828521134
10S-palmitoylationWPCITRACCIARFWN
CHHHHHHHHHHHHHH		1.2328521134
11S-palmitoylationPCITRACCIARFWNQ
HHHHHHHHHHHHHHH		2.3828521134
21AcetylationRFWNQLDKADIAVPL
HHHHHHCCCCCEEEE		57.4622902405
86PhosphorylationTGPAPGPSGDRETAA
HCCCCCCCCCHHHCC		60.2825403869
98PhosphorylationTAAAPGRSGLGLGAA
HCCCCCCCCCCCCCC		44.26-
106PhosphorylationGLGLGAASGSTSGSG
CCCCCCCCCCCCCCC		32.5125403869
108PhosphorylationGLGAASGSTSGSGPA
CCCCCCCCCCCCCCC		19.5325403869
109PhosphorylationLGAASGSTSGSGPAD
CCCCCCCCCCCCCCH		40.4025403869
110PhosphorylationGAASGSTSGSGPADS
CCCCCCCCCCCCCHH		32.4325403869
112PhosphorylationASGSTSGSGPADSVM
CCCCCCCCCCCHHHH		41.1725403869
127UbiquitinationRQDYRAWKVQRPEPS
HHHHHHHHCCCCCCC		27.75-
141PhosphorylationSCRPRSEYQPSDAPF
CCCCCCCCCCCCCCC		27.28-
174AcetylationGDHPWIPKPVQIPAT
CCCCCCCCCEECCCC		49.0022902405
185PhosphorylationIPATSQPSPPVLGMP
CCCCCCCCCCCCCCC		33.9122673903
198PhosphorylationMPKRRPQSQERGPIQ
CCCCCCCCCCCCCEE		36.3725403869
207PhosphorylationERGPIQLSADARDPE
CCCCEEEECCCCCCC		14.0227097102
226UbiquitinationAGVPAAGKASGADQR
CCCCCCCCCCCCCHH		34.35-
235PhosphorylationSGADQRDTRRKAGPA
CCCCHHHHHHHCCCE		34.2625403869
238UbiquitinationDQRDTRRKAGPAWMV
CHHHHHHHCCCEEEE		55.17-
254AcetylationRTEGHEEKPLPPAQS
CCCCCCCCCCCCCHH		49.2022902405
254UbiquitinationRTEGHEEKPLPPAQS
CCCCCCCCCCCCCHH		49.20-
272UbiquitinationEGGPAAGKASGADQR
CCCCCCCCCCCCCHH		34.35-
281PhosphorylationSGADQRDTRRKAGPA
CCCCHHHHHHHCCCE		34.2625403869
300UbiquitinationRTEGHEEKPLPPAQS
CCCCCCCCCCCCCHH		49.20-
300AcetylationRTEGHEEKPLPPAQS
CCCCCCCCCCCCCHH		49.207770353
318UbiquitinationEGGPAAGKASGADQR
CCCCCCCCCCCCCHH		34.35-
327PhosphorylationSGADQRDTRRKAGPA
CCCCHHHHHHHCCCE		34.2625403869
373PhosphorylationSGADQRDTRRKAGPA
CCCCHHHHHHHCCCE		34.2625403869
410UbiquitinationEGGPAAGKASGADER
CCCCCCCCCCCCCHH		34.35-
432PhosphorylationPAWMVRRSEGHEQTT
CEEEEECCCCCCCCC		37.0525403869
452UbiquitinationGTGPEGGKGRAVADA
CCCCCCCHHHHHHHH		56.96-
487AcetylationFRAWTDIKPVKPIKA
EEEECCCCCCCCCCC		46.7122902405
487UbiquitinationFRAWTDIKPVKPIKA
EEEECCCCCCCCCCC		46.71-
490UbiquitinationWTDIKPVKPIKAKPQ
ECCCCCCCCCCCCCC		49.94-
490AcetylationWTDIKPVKPIKAKPQ
ECCCCCCCCCCCCCC		49.9422902405
521AcetylationQFKGEASKPTTADNK
EECCCCCCCCCCCCC		54.1322902405
521UbiquitinationQFKGEASKPTTADNK
EECCCCCCCCCCCCC		54.13-
528UbiquitinationKPTTADNKVVDRRRI
CCCCCCCCEECHHHH		44.15-
537PhosphorylationVDRRRIRSLYSEPFK
ECHHHHHHHHCCCCC		29.3223984901
558UbiquitinationKPSVQSSKPKKTSTS
CCCCCCCCCCCCCCC		67.13-
590PhosphorylationAKKKTTESPSATKPD
HHCCCCCCCCCCCCC		23.2830411139
592PhosphorylationKKTTESPSATKPDDK
CCCCCCCCCCCCCHH		58.8228432305
594PhosphorylationTTESPSATKPDDKEQ
CCCCCCCCCCCHHHH		47.66-
681PhosphorylationPGSLKGQSPTAPGPP
CCCCCCCCCCCCCCC		32.6523984901
683PhosphorylationSLKGQSPTAPGPPKD
CCCCCCCCCCCCCCC		51.2122108457
709PhosphorylationLGPVAPASVKDQDHM
CCCCCCCCCCCCHHH		28.7422673903
736PhosphorylationLAPAKAQSPLLPEPL
CCCCCCCCCCCCCCC		23.5230411139
747PhosphorylationPEPLKNQSPVVPARA
CCCCCCCCCCCCCCC		29.1128432305
795PhosphorylationRRKDQNASIMASLKN
HHHCCCCHHHHHHCC		22.0525575281
799PhosphorylationQNASIMASLKNEAPV
CCCHHHHHHCCCCCC		23.6125575281
930PhosphorylationPRGPQLPTVSPSPPV
CCCCCCCCCCCCCCE		42.0628551015
932PhosphorylationGPQLPTVSPSPPVMI
CCCCCCCCCCCCEEC		23.3428551015
934PhosphorylationQLPTVSPSPPVMIPT
CCCCCCCCCCEECCC		34.0427097102
941PhosphorylationSPPVMIPTVPHAEYI
CCCEECCCCCCHHHC		35.4327097102
947PhosphorylationPTVPHAEYIEGSP--
CCCCCHHHCCCCC--		12.6927097102
951PhosphorylationHAEYIEGSP------
CHHHCCCCC------		18.0430411139
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MAP6_RAT !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MAP6_RAT !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MAP6_RAT !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of MAP6_RAT !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MAP6_RAT

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Related Literatures of Post-Translational Modification

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