| UniProt ID | MANEL_HUMAN | |
|---|---|---|
| UniProt AC | Q5VSG8 | |
| Protein Name | Glycoprotein endo-alpha-1,2-mannosidase-like protein | |
| Gene Name | MANEAL | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 457 | |
| Subcellular Localization |
Golgi apparatus membrane Single-pass type II membrane protein. |
|
| Protein Description | ||
| Protein Sequence | MARRRRRACIALFLVLLFAFGTLMGLRTLKAPDGLPALGPGLELAPFERRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGPAPAEAEPAPVQSLRVYSDLHAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSSRDPEVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPSDDLVPAILDTAHQYSIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRYKNSMGKSLPLFYIYDSYLTSPEAWAHLLTPNGPHSIRNTPYDGVFIALLVEEGHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDANNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAIPKKTPTRLYLDYLPHQPSLYLELTRRWAEHFIKEKEQWLM | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 30 | Ubiquitination | LMGLRTLKAPDGLPA HHCHHHCCCCCCCCC | 58.21 | - | |
| 77 | Phosphorylation | PPPPPPRTADPGGSP CCCCCCCCCCCCCCC | 40.98 | 27732954 | |
| 83 | Phosphorylation | RTADPGGSPGPAPAE CCCCCCCCCCCCCCC | 32.38 | 21815630 | |
| 83 | O-linked_Glycosylation | RTADPGGSPGPAPAE CCCCCCCCCCCCCCC | 32.38 | OGP | |
| 140 | Phosphorylation | WDPKISASYPRGRHS CCCCCCCCCCCCCCC | 28.95 | 24719451 | |
| 141 | Phosphorylation | DPKISASYPRGRHSP CCCCCCCCCCCCCCC | 9.18 | 22210691 | |
| 191 | Phosphorylation | GVLVLSWYPPGMADD HEEEEECCCCCCCCC | 9.00 | 25332170 | |
| 203 | Phosphorylation | ADDNGEPSDDLVPAI CCCCCCCCCHHHHHH | 39.18 | 25332170 | |
| 242 | Phosphorylation | TVHDNIKYIIDTYGS EEECCEEEEEECCCC | 10.18 | 22461510 | |
| 246 | Phosphorylation | NIKYIIDTYGSHGAF CEEEEEECCCCCCCH | 21.26 | 22461510 | |
| 247 | Phosphorylation | IKYIIDTYGSHGAFY EEEEEECCCCCCCHH | 16.94 | 22461510 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MANEL_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MANEL_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MANEL_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of MANEL_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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