MAF1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MAF1_SCHPO
• UniProt AC: O14109
• Protein Name: Repressor of RNA polymerase III transcription maf1
• Gene Name: maf1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 238
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Mediator of diverse signals that repress RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA..
• Protein Sequence: MKFLELADLDTVNNALSFDADDCRIRGKCELYTTKSTNSDKKLFKAIENRCQEDLFALSSSKSPEYAFSLTQQSPFGPLDQSSSRRTFMYIVATLNASYPDHDFSSLQPTDFYKEPSLSRVVDSVNSTLNNIGRGRLSVNGIWEIIDRHINLSDCSVYSYTPDSDSDPYGDDALIWGMSYFFFNKNMKRMLYLSLHGLGKEVSGRNRYGNDDDSVFTPLADDAEPSDFDDDWVANMDD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
59	Phosphorylation	QEDLFALSSSKSPEY HHHHHHHCCCCCHHH		21712547
60	Phosphorylation	EDLFALSSSKSPEYA HHHHHHCCCCCHHHE		21712547
61	Phosphorylation	DLFALSSSKSPEYAF HHHHHCCCCCHHHEE		21712547
63	Phosphorylation	FALSSSKSPEYAFSL HHHCCCCCHHHEEEC		29996109
66	Phosphorylation	SSSKSPEYAFSLTQQ CCCCCHHHEEECCCC		29996109
74	Phosphorylation	AFSLTQQSPFGPLDQ EEECCCCCCCCCCCC		29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MAF1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MAF1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MAF1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRM1_SCHPO	trm1	genetic	26720005

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.