LZTR1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LZTR1_MOUSE
• UniProt AC: Q9CQ33
• Protein Name: Leucine-zipper-like transcriptional regulator 1
• Gene Name: Lztr1
• Organism: Mus musculus (Mouse).
• Sequence Length: 837
• Protein Description: Probable transcriptional regulator that may play a crucial role in embryogenesis..
• Protein Sequence: MAGSGGPIGSGALTGGVRSKVAPSVDFDHSCSDSVEYLTLNFGPFETVHRWRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQRRYGHTMVAFDRHLYVFGGAADNTLPNELHCYDVDFQTWEVVQPSSDSEVGGAEMPERASSSEDASTLTSEERSSFKKSRDVFGLDFGTTSAKQPVHLASELPSGRLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWEGRQFCDVEFVLGEKEECVQGHVAIVTARSRWLRRKIVQAQEWLAQKLEEDGALAPKEAPGPAVGRARPPLLRVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQYIEASVDLQNVLVVCESAARLQLGQLKEHCLNFIVKESHFNQVIMMKEFERLSSPLIVEIVRRKQQPPPRTPSDQPVDIGTSLIQDMKAYLEGAGSEFCDITLLLDGQPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLRYIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAADKTQALDMKRHCLHIIVHQFTKVSKLPTLRLLSQQLLLDIIDSLASHISDKQCAELGADI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAGSGGPIG ------CCCCCCCCC	22.36	-
116	Phosphorylation	GTPPAPRYHHSAVVY CCCCCCCCCCCEEEE	11.65	-
345	Phosphorylation	ASSSEDASTLTSEER CCCCCCHHHCCHHHH	35.95	28066266
346	Phosphorylation	SSSEDASTLTSEERS CCCCCHHHCCHHHHH	35.46	28066266
348	Phosphorylation	SEDASTLTSEERSSF CCCHHHCCHHHHHHH	33.89	28066266
349	Phosphorylation	EDASTLTSEERSSFK CCHHHCCHHHHHHHH	40.34	28066266
354	Phosphorylation	LTSEERSSFKKSRDV CCHHHHHHHHHHHCE	47.51	29899451
372	Ubiquitination	DFGTTSAKQPVHLAS CCCCCCCCCCCCHHH	55.70	22790023
372 (in isoform 2)	Ubiquitination	-	55.70	22790023
529	Acetylation	MQFLYTDKIKYPRKG HHHHHCCCCCCCCCC	33.04	23806337
529	Succinylation	MQFLYTDKIKYPRKG HHHHHCCCCCCCCCC	33.04	23806337
638	Phosphorylation	QPPPRTPSDQPVDIG CCCCCCCCCCCCCCC	48.54	25338131

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LZTR1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LZTR1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LZTR1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of LZTR1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.