LRRN1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRRN1_RAT
• UniProt AC: Q32Q07
• Protein Name: Leucine-rich repeat neuronal protein 1
• Gene Name: Lrrn1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 716
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Sequence: MARLSPGKAACWMVLGLLIPSLTESSILNSECPQLCVCEIRPWFTPQSTYREATTVDCNDLRLTRIPGNLSSDTQVLLLQSNNIAKTVDELQQLFNLTELDFSQNNFTNIKEVGLANLTQLTTLHLEENQISEMTDYCLQDLSNLQELYINHNQISSISANAFSGLKNLLRLHLNSNKLKVIDSRWFDSTPNLEILMIGENPVIGILDMNFRPLSNLRSLVLAGMYLTDIPGNALVGLDSLESLSFYDNKLIKVPQLALQKVPNLKFLDLNKNPIHKIQEGDFKNMLRLKELGINNMGELVSVDRYALDNLPELTKLEATNNPKLSYIHRLAFRSVPALESLMLNNNALNAVYQKTVESLPNLREISIHSNPLRCDCVIHWINSNKTNIRFMEPLSMFCAMPPEYRGQQVKEVLIQDSSEQCLPMISHDTFPNHLNMDIGTTLFLDCRAMAEPEPEIYWVTPIGNKITVETLSDKYKLSSEGTLEIANIQIEDSGRYTCVAQNVQGADTRVATIKVNGTLLDGAQVLKIYVKQTESHSILVSWKVNSNVMTSNLKWSSATMKIDNPHITYTARVPVDVHEYNLTHLQPSTDYEVCLTVSNIHQQTQKSCVNVTTKTAAFALDISDHETSTALAAVMGSMFAVISLASIAIYIAKRFKRKNYHHSLKKYMQKTSSIPLNELYPPLINLWEGDSDKDKDGSADTKPTQVDTSRSYYMW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
69	N-linked_Glycosylation	RLTRIPGNLSSDTQV EEEECCCCCCCCCEE	31.25	-
96	N-linked_Glycosylation	DELQQLFNLTELDFS HHHHHHHCCCCCCCC	55.43	-
106	N-linked_Glycosylation	ELDFSQNNFTNIKEV CCCCCCCCCCCHHHH	37.17	-
117	N-linked_Glycosylation	IKEVGLANLTQLTTL HHHHCCCCCHHEEEE	48.98	-
385	N-linked_Glycosylation	VIHWINSNKTNIRFM EEEEECCCCCEEEEE	51.16	-
517	N-linked_Glycosylation	RVATIKVNGTLLDGA EEEEEEECCEEECCC	32.50	-
538	Phosphorylation	VKQTESHSILVSWKV EEECCCCEEEEEEEE	27.22	16641100
542	Phosphorylation	ESHSILVSWKVNSNV CCCEEEEEEEECCCC	20.10	16641100
582	N-linked_Glycosylation	PVDVHEYNLTHLQPS CCEEEECCCCCCCCC	35.16	-
611	N-linked_Glycosylation	QTQKSCVNVTTKTAA HHHHHCCCCCCCCEE	29.73	-
703	Ubiquitination	KDGSADTKPTQVDTS CCCCCCCCCCEEECC	46.76	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRRN1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRRN1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRRN1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of LRRN1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.