LRRC3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRRC3_HUMAN
• UniProt AC: Q9BY71
• Protein Name: Leucine-rich repeat-containing protein 3
• Gene Name: LRRC3
• Organism: Homo sapiens (Human).
• Sequence Length: 257
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MGTVRPPRPSLLLVSTRESCLFLLFCLHLGAACPQPCRCPDHAGAVAVFCSLRGLQEVPEDIPANTVLLKLDANKISHLPDGAFQHLHRLRELDLSHNAIEAIGSATFAGLAGGLRLLDLSYNRIQRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSVQEEFVGKPLVQALDAGASLCSVPHRTTDVAMLVTMFGWFAMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPASKDPIGPGP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MGTVRPPRPS -----CCCCCCCCCC	16.43	26074081
10	Phosphorylation	TVRPPRPSLLLVSTR CCCCCCCCEEEEECH	32.69	24043423
15	Phosphorylation	RPSLLLVSTRESCLF CCCEEEEECHHHHHH	23.01	24043423
16	Phosphorylation	PSLLLVSTRESCLFL CCEEEEECHHHHHHH	30.86	24043423
241	Ubiquitination	RRHLEYLKSLPSAPA HHHHHHHHHCCCCCC	49.39	23503661
250	Ubiquitination	LPSAPASKDPIGPGP CCCCCCCCCCCCCCC	70.41	21906983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRRC3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRRC3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRRC3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of LRRC3_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.