LRRC2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LRRC2_HUMAN
• UniProt AC: Q9BYS8
• Protein Name: Leucine-rich repeat-containing protein 2
• Gene Name: LRRC2
• Organism: Homo sapiens (Human).
• Sequence Length: 371
• Protein Sequence: MGHKVVVFDISVIRALWETRVKKHKAWQKKEVERLEKSALEKIKEEWNFVAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPIDNAQCEDGNEIMESERDRQHFDKEVMKAYIEDLKERESVPSYTTKVSFSLQL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	KVVVFDISVIRALWE CEEEEEHHHHHHHHH	17.21	24719451
88	Phosphorylation	RNTLTRQSSLPKDRG HCCCCCCCCCCCCCC	30.47	23927012
89	Phosphorylation	NTLTRQSSLPKDRGK CCCCCCCCCCCCCCC	40.11	26437602
98	Phosphorylation	PKDRGKRSSAFVFEL CCCCCCCCCEEEEEE	29.51	-
99	Phosphorylation	KDRGKRSSAFVFELS CCCCCCCCEEEEEEC	29.74	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LRRC2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LRRC2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LRRC2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of LRRC2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.