dbPTM

LRRC1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LRRC1_MOUSE
UniProt AC	Q80VQ1
Protein Name	Leucine-rich repeat-containing protein 1
Gene Name	Lrrc1
Organism	Mus musculus (Mouse).
Sequence Length	524
Subcellular Localization	Cytoplasm. Membrane Peripheral membrane protein. Localized at the basolateral side of epithelial cells..
Protein Description
Protein Sequence	MFHCIPLWRCNRHVEAIDKRHCSLVYVPEEIYRYARSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNDIPEIPESIAFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEEISGLTSLTYLVISQNLLETIPEGIGKLKKLSILKLDQNRLTQLPEAIGDCENLTELVLTENRLLTLPKSIGKLKKLSNLNADRNKLVSLPKEIGGCCSLTMFCIRDNRLTRLPAEVSQAVELHVLDVAGNRLHHLPLSLTTLKLKALWLSDNQSQPLLTFQTDIDRATGEKILTCVLLPQMPSEPICQESLPRCGALESLVTDMSEEAWNDRSVHRVSAIRFLEDEKDEDENETRTLQRRATPHPGELKNMKKTVENLRNDMNAAKGLDSNKNEVNHAAERVTTSV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	S-palmitoylation	----MFHCIPLWRCN ----CCCCEECCCCC	2.04	28680068
37	Phosphorylation	EIYRYARSLEELLLD HHHHHHHCHHHHHCC	31.77	29472430
323	Ubiquitination	NLNADRNKLVSLPKE CCCCCHHHHHCCCHH	51.68	-
456	Phosphorylation	DRSVHRVSAIRFLED CCCCHHHEEEEEHHC	20.24	28507225
480	Phosphorylation	RTLQRRATPHPGELK HHHHHHCCCCCCHHH	21.96	25266776

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LRRC1_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LRRC1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LRRC1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of LRRC1_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LRRC1_MOUSE

Related Literatures of Post-Translational Modification