| UniProt ID | LRP11_HUMAN | |
|---|---|---|
| UniProt AC | Q86VZ4 | |
| Protein Name | Low-density lipoprotein receptor-related protein 11 | |
| Gene Name | LRP11 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 500 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein . |
|
| Protein Description | ||
| Protein Sequence | MASVAQESAGSQRRLPPRHGALRGLLLLCLWLPSGRAALPPAAPLSELHAQLSGVEQLLEEFRRQLQQERPQEELELELRAGGGPQEDCPGPGSGGYSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSEPRCSVAVVELPRRPAPPAAVLGCYLFNCTARGRNVCKFALHSGYSSYSLSRAPDGAALATARASPRQEKDAPPLSKAGQDVVLHLPTDGVVLDGRESTDDHAIVQYEWALLQGDPSVDMKVPQSGTLKLSHLQEGTYTFQLTVTDTAGQRSSDNVSVTVLRAAYSTGGCLHTCSRYHFFCDDGCCIDITLACDGVQQCPDGSDEDFCQNLGLDRKMVTHTAASPALPRTTGPSEDAGGDSLVEKSQKATAPNKPPALSNTEKRNHSAFWGPESQIIPVMPDSSSSGKNRKEESYIFESKGDGGGGEHPAPETGAVLPLALGLAITALLLLMVACRLRLVKQKLKKARPITSEESDYLINGMYL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 8 | Phosphorylation | MASVAQESAGSQRRL CCCHHHHCCCCCCCC | 26.33 | 23312004 | |
| 11 | Phosphorylation | VAQESAGSQRRLPPR HHHHCCCCCCCCCCC | 21.89 | 25690035 | |
| 108 | Ubiquitination | PDAIIRTKDSLAAGA CCCEEECCCCHHHCC | 35.16 | - | |
| 116 | Phosphorylation | DSLAAGASFLRAPAA CCHHHCCHHHHHHHH | 24.72 | 24719451 | |
| 164 | N-linked_Glycosylation | VLGCYLFNCTARGRN HEEEEEECCCCCCCC | 21.45 | UniProtKB CARBOHYD | |
| 197 | O-linked_Glycosylation | PDGAALATARASPRQ CCHHHHHHHCCCCCC | 19.95 | 55835113 | |
| 209 (in isoform 2) | O-linked_Glycosylation | - | 40.26 | OGP | |
| 212 | Phosphorylation | EKDAPPLSKAGQDVV CCCCCCCHHCCCCEE | 26.66 | - | |
| 213 (in isoform 1) | Ubiquitination | - | 65.31 | 21906983 | |
| 213 | Ubiquitination | KDAPPLSKAGQDVVL CCCCCCHHCCCCEEE | 65.31 | 21906983 | |
| 257 | Ubiquitination | GDPSVDMKVPQSGTL CCCCCCEECCCCCEE | 46.42 | - | |
| 288 | O-linked_Glycosylation | TDTAGQRSSDNVSVT EECCCCCCCCCEEEE | 33.87 | 55826017 | |
| 289 | O-linked_Glycosylation | DTAGQRSSDNVSVTV ECCCCCCCCCEEEEE | 35.08 | 55826023 | |
| 291 | N-linked_Glycosylation | AGQRSSDNVSVTVLR CCCCCCCCEEEEEEE | 29.88 | UniProtKB CARBOHYD | |
| 293 | O-linked_Glycosylation | QRSSDNVSVTVLRAA CCCCCCEEEEEEEHH | 20.51 | 55826029 | |
| 295 | O-linked_Glycosylation | SSDNVSVTVLRAAYS CCCCEEEEEEEHHHH | 13.30 | 55826035 | |
| 302 | O-linked_Glycosylation | TVLRAAYSTGGCLHT EEEEHHHHCCCCCCE | 18.82 | 55825093 | |
| 303 | O-linked_Glycosylation | VLRAAYSTGGCLHTC EEEHHHHCCCCCCEE | 25.56 | 55825099 | |
| 311 | O-linked_Glycosylation | GGCLHTCSRYHFFCD CCCCCEECCCEEEEC | 36.71 | 55825105 | |
| 355 | Phosphorylation | GLDRKMVTHTAASPA CCCHHHHCCCCCCCC | 15.26 | - | |
| 355 | O-linked_Glycosylation | GLDRKMVTHTAASPA CCCHHHHCCCCCCCC | 15.26 | 55825637 | |
| 357 | Phosphorylation | DRKMVTHTAASPALP CHHHHCCCCCCCCCC | 17.98 | - | |
| 357 | O-linked_Glycosylation | DRKMVTHTAASPALP CHHHHCCCCCCCCCC | 17.98 | 55825643 | |
| 360 | O-linked_Glycosylation | MVTHTAASPALPRTT HHCCCCCCCCCCCCC | 14.29 | 46245625 | |
| 360 | Phosphorylation | MVTHTAASPALPRTT HHCCCCCCCCCCCCC | 14.29 | - | |
| 366 | Phosphorylation | ASPALPRTTGPSEDA CCCCCCCCCCCCCCC | 33.88 | - | |
| 366 | O-linked_Glycosylation | ASPALPRTTGPSEDA CCCCCCCCCCCCCCC | 33.88 | 55834197 | |
| 367 | O-linked_Glycosylation | SPALPRTTGPSEDAG CCCCCCCCCCCCCCC | 48.66 | 46245629 | |
| 367 | Phosphorylation | SPALPRTTGPSEDAG CCCCCCCCCCCCCCC | 48.66 | - | |
| 370 | Phosphorylation | LPRTTGPSEDAGGDS CCCCCCCCCCCCCCC | 49.83 | - | |
| 381 (in isoform 1) | Ubiquitination | - | 51.19 | 21906983 | |
| 381 | Ubiquitination | GGDSLVEKSQKATAP CCCCHHHHHHCCCCC | 51.19 | 2190698 | |
| 386 | O-linked_Glycosylation | VEKSQKATAPNKPPA HHHHHCCCCCCCCCC | 50.08 | 55829791 | |
| 390 | Ubiquitination | QKATAPNKPPALSNT HCCCCCCCCCCCCCC | 51.85 | - | |
| 395 | O-linked_Glycosylation | PNKPPALSNTEKRNH CCCCCCCCCCCCCCC | 43.76 | OGP | |
| 397 | O-linked_Glycosylation | KPPALSNTEKRNHSA CCCCCCCCCCCCCCC | 39.24 | 55829797 | |
| 399 | Ubiquitination | PALSNTEKRNHSAFW CCCCCCCCCCCCCCC | 57.36 | - | |
| 401 | N-linked_Glycosylation | LSNTEKRNHSAFWGP CCCCCCCCCCCCCCC | 44.53 | UniProtKB CARBOHYD | |
| 410 | O-linked_Glycosylation | SAFWGPESQIIPVMP CCCCCCHHHEEEECC | 29.79 | OGP | |
| 491 | Phosphorylation | RPITSEESDYLINGM CCCCCHHHCCEECCC | 27.75 | 25884760 | |
| 493 | Phosphorylation | ITSEESDYLINGMYL CCCHHHCCEECCCCC | 20.82 | - | |
| 499 | Phosphorylation | DYLINGMYL------ CCEECCCCC------ | 15.62 | 27259358 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LRP11_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LRP11_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LRP11_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of LRP11_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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