dbPTM

LRC3B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LRC3B_HUMAN
UniProt AC	Q96PB8
Protein Name	Leucine-rich repeat-containing protein 3B
Gene Name	LRRC3B
Organism	Homo sapiens (Human).
Sequence Length	259
Subcellular Localization	Membrane Single-pass membrane protein .
Protein Description
Protein Sequence	MNLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMASNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	VDLWLTRSLSMCLLL HHHHHHHHHHHHHHH	21.40	29038488
13	Phosphorylation	LWLTRSLSMCLLLQS HHHHHHHHHHHHHHH	14.54	29038488
20	Phosphorylation	SMCLLLQSFVLMILC HHHHHHHHHHHHHHH	19.79	29038488
32	Phosphorylation	ILCFHSASMCPKGCL HHHHHCCCCCCCCCE	24.75	29038488
47	N-linked_Glycosylation	CSSSGGLNVTCSNAN ECCCCCEEEEECCCC	30.26	UniProtKB CARBOHYD
70	Phosphorylation	PPETVLLYLDSNQIT CCCCEEEEECCCCCC	12.33	28857561
73	Phosphorylation	TVLLYLDSNQITSIP CEEEEECCCCCCCCC	28.21	28857561
94	N-linked_Glycosylation	LHQLRVLNLSKNGIE HHHHHHHCCCCCCCC	39.14	UniProtKB CARBOHYD
204	Phosphorylation	LPKKTTDYAMLVTMF CCCCCCHHHHHHHHH	7.57	-
219	Phosphorylation	GWFTMVISYVVYYVR HHHHHHHHHHHHHHH	10.64	22210691
220	Phosphorylation	WFTMVISYVVYYVRQ HHHHHHHHHHHHHHC	5.25	-
223	Phosphorylation	MVISYVVYYVRQNQE HHHHHHHHHHHCCHH	6.03	-
224	Phosphorylation	VISYVVYYVRQNQED HHHHHHHHHHCCHHH	4.23	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LRC3B_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LRC3B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LRC3B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of LRC3B_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LRC3B_HUMAN

Related Literatures of Post-Translational Modification