dbPTM

LRC24_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LRC24_HUMAN
UniProt AC	Q50LG9
Protein Name	Leucine-rich repeat-containing protein 24
Gene Name	LRRC24
Organism	Homo sapiens (Human).
Sequence Length	513
Subcellular Localization	Membrane Single-pass membrane protein .
Protein Description
Protein Sequence	MALRAPALLPLLLLLLPLRAAGCPAACRCYSATVECGALRLRVVPLGIPPGTQTLFLQDNNIARLEPGALAPLAALRRLYLHNNSLRALEAGAFRAQPRLLELALTSNRLRGLRSGAFVGLAQLRVLYLAGNQLARLLDFTFLHLPRLQELHLQENSIELLEDQALAGLSSLALLDLSRNQLGTISREALQPLASLQVLRLTENPWRCDCALHWLGAWIKEGGQRLLTSRDRKIMCAEPPRLALQSLLDVSHSSLICIPPSVHVQPLELTANLGEDLRVACQASGYPQPLVTWRKVPQPREGRPRAQAQLEGGLLGLGGHSASDTGSGMLFLSNITLAHAGKYECEASNAGGAARVPFRLLVNASRQQPQQPAQPPPPAARPAGSEPRPEAGSMAFRALGVATQTAIAAAIALLALTALLLVAMICRRRRRRKKARGPPGEGALFVNDYLDGPCTFAQLEELRDERGHEMFVINRSKPLFAEGPAEAPADCGPEQGAGPGLRVPPPVAYEIHC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
228	Phosphorylation	EGGQRLLTSRDRKIM HHHHEEECCCCCEEC	26.72	24719451
284	Phosphorylation	LRVACQASGYPQPLV HHHHHHCCCCCCCEE	17.00	23663014
286	Phosphorylation	VACQASGYPQPLVTW HHHHCCCCCCCEEEE	9.01	23663014
292	Phosphorylation	GYPQPLVTWRKVPQP CCCCCEEEEEECCCC	27.51	23663014
334	N-linked_Glycosylation	SGMLFLSNITLAHAG CCEEEECCEEEEECC	33.15	UniProtKB CARBOHYD
363	N-linked_Glycosylation	VPFRLLVNASRQQPQ CCEEEEEECCCCCCC	31.97	UniProtKB CARBOHYD
476	Phosphorylation	EMFVINRSKPLFAEG EEEEEECCCCCCCCC	33.85	24719451
509	Phosphorylation	RVPPPVAYEIHC--- CCCCCCEEEECC---	18.69	25884760

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LRC24_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LRC24_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LRC24_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of LRC24_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LRC24_HUMAN

Related Literatures of Post-Translational Modification