LR37B_HUMAN - dbPTM
LR37B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LR37B_HUMAN
UniProt AC Q96QE4
Protein Name Leucine-rich repeat-containing protein 37B
Gene Name LRRC37B
Organism Homo sapiens (Human).
Sequence Length 947
Subcellular Localization Membrane
Single-pass type I membrane protein .
Protein Description
Protein Sequence MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESPHAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQDLNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVSRPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTSTNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSENYLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQAWHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLILPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKALNVEWDTDQQKTNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILIIIFCLIEVNSHKRASEKYKDNPSISGA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
221PhosphorylationKPQRQKQTLPDDYLS
CHHHHHCCCCCCCCC		47.4924043423
226PhosphorylationKQTLPDDYLSMDTLY
HCCCCCCCCCCCCCC		14.2024043423
228PhosphorylationTLPDDYLSMDTLYPG
CCCCCCCCCCCCCCC		14.3730622161
231PhosphorylationDDYLSMDTLYPGSLP
CCCCCCCCCCCCCCC		21.3930622161
233PhosphorylationYLSMDTLYPGSLPPE
CCCCCCCCCCCCCHH		13.9830622161
236PhosphorylationMDTLYPGSLPPELRV
CCCCCCCCCCHHHCC		32.9530622161
358N-linked_GlycosylationTMTSEPKNETESTQA
EECCCCCCCCCCCCC		72.62UniProtKB CARBOHYD
409PhosphorylationDKGQAQHSHLTEATV
CCCCCCCCCCCEEEE		14.2224043423
412PhosphorylationQAQHSHLTEATVQPL
CCCCCCCCEEEECCE		20.3924043423
415PhosphorylationHSHLTEATVQPLDLE
CCCCCEEEECCEEEE		17.2824043423
424PhosphorylationQPLDLELSITTEPTT
CCEEEEEEEECCCCC		14.4424043423
426PhosphorylationLDLELSITTEPTTEV
EEEEEEEECCCCCCC		23.0224043423
427PhosphorylationDLELSITTEPTTEVK
EEEEEEECCCCCCCC		37.9924043423
430PhosphorylationLSITTEPTTEVKPSP
EEEECCCCCCCCCCC		29.3824043423
431PhosphorylationSITTEPTTEVKPSPT
EEECCCCCCCCCCCC		49.8824043423
497PhosphorylationGPPTKLESSQDSLVQ
CCCCCCCCCCHHHHC		43.6825693802
498PhosphorylationPPTKLESSQDSLVQS
CCCCCCCCCHHHHCC		28.7325693802
501PhosphorylationKLESSQDSLVQSETA
CCCCCCHHHHCCCCC		23.8525693802
590PhosphorylationKLILSENYLTELPKD
HHHCCCCCCCCCCCC		15.7929396449
592PhosphorylationILSENYLTELPKDSF
HCCCCCCCCCCCCCC		25.7229396449
682PhosphorylationFELPALKYLDMGTTH
HHCCHHHCCCCCCCE		14.58-
688PhosphorylationKYLDMGTTHITLTTL
HCCCCCCCEEEHHHH		12.92-
691PhosphorylationDMGTTHITLTTLKNI
CCCCCEEEHHHHHHH		15.50-
733AcetylationEAVCKTVKLHCNTAC
HHHHHHHHHHCCCCH		37.4325038526
789N-linked_GlycosylationPSDSSGINLSGFGGD
CCCCCCCCCCCCCCC		31.51UniProtKB CARBOHYD
800UbiquitinationFGGDQLEIQLTEQLR
CCCCCEEEECHHHHH		5.7421906983
809UbiquitinationLTEQLRSLIPNEDVR
CHHHHHHCCCCHHHH		6.4521906983
820PhosphorylationEDVRKFMSHVIRTLK
HHHHHHHHHHHHHHH		20.10-
821UbiquitinationDVRKFMSHVIRTLKM
HHHHHHHHHHHHHHH		13.7721906983
831PhosphorylationRTLKMECSETHVQGS
HHHHHHHHHHHCCHH		32.02-
833PhosphorylationLKMECSETHVQGSCA
HHHHHHHHHCCHHHH		15.85-
838PhosphorylationSETHVQGSCAKLMLR
HHHHCCHHHHHHHHH		8.20-
851UbiquitinationLRTGLLMKLLSEQQE
HHHHHHHHHHHHHHH		46.3621906983
860UbiquitinationLSEQQEAKALNVEWD
HHHHHHHHHCCCCCC		53.2921906983
872UbiquitinationEWDTDQQKTNYINEN
CCCCHHHHHHHHHHH		32.862190698
873PhosphorylationWDTDQQKTNYINENM
CCCHHHHHHHHHHHH		28.9930622161
875PhosphorylationTDQQKTNYINENMEQ
CHHHHHHHHHHHHHH		15.4530622161
902PhosphorylationKEVPGDDYKNKLIFA
HHCCCCHHHHHHHHH		22.6218083107
943PhosphorylationEKYKDNPSISGA---
HHHCCCCCCCCC---		35.3230622161
945PhosphorylationYKDNPSISGA-----
HCCCCCCCCC-----		32.7630622161
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LR37B_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LR37B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LR37B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of LR37B_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LR37B_HUMAN

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Related Literatures of Post-Translational Modification

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