LPP60_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LPP60_HUMAN
• UniProt AC: Q86U10
• Protein Name: 60 kDa lysophospholipase
• Gene Name: ASPG
• Organism: Homo sapiens (Human).
• Sequence Length: 573
• Protein Description: Exhibits lysophospholipase, transacylase, PAF acetylhydrolase and asparaginase activities..
• Protein Sequence: MARAVGPERRLLAVYTGGTIGMRSELGVLVPGTGLAAILRTLPMFHDEEHARARGLSEDTLVLPPASRNQRILYTVLECQPLFDSSDMTIAEWVCLAQTIKRHYEQYHGFVVIHGTDTMAFAASMLSFMLENLQKTVILTGAQVPIHALWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRATKVDARRFAAFCSPNLLPLATVGADITINRELVRKVDGKAGLVVHSSMEQDVGLLRLYPGIPAALVRAFLQPPLKGVVMETFGSGNGPTKPDLLQELRVATERGLVIVNCTHCLQGAVTTDYAAGMAMAGAGVISGFDMTSEAALAKLSYVLGQPGLSLDVRKELLTKDLRGEMTPPSVEERRPSLQGNTLGGGVSWLLSLSGSQEADALRNALVPSLACAAAHAGDVEALQALVELGSDLGLVDFNGQTPLHAAARGGHTEAVTMLLQRGVDVNTRDTDGFSPLLLAVRGRHPGVIGLLREAGASLSTQELEEAGTELCRLAYRADLEGLQVWWQAGADLGQPGYDGHSALHVAEAAGNLAVVAFLQSLEGAVGAQAPCPEVLPGV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
136	Phosphorylation	MLENLQKTVILTGAQ HHHHHHCEEEECCCC	10.38	24719451
136	Phosphorylation	MLENLQKTVILTGAQ HHHHHHCEEEECCCC	10.38	24719451
140	Phosphorylation	LQKTVILTGAQVPIH HHCEEEECCCCCCCC	21.24	24719451
140	Phosphorylation	LQKTVILTGAQVPIH HHCEEEECCCCCCCC	21.24	24719451
232	Phosphorylation	KAGLVVHSSMEQDVG CEEEEEECCCCCCCC	21.55	23663014
233	Phosphorylation	AGLVVHSSMEQDVGL EEEEEECCCCCCCCH	16.09	23663014
371	Phosphorylation	SVEERRPSLQGNTLG CHHHHCCCCCCCCCC	31.36	28857561
376	Phosphorylation	RPSLQGNTLGGGVSW CCCCCCCCCCCHHHH	33.34	28857561
382	Phosphorylation	NTLGGGVSWLLSLSG CCCCCHHHHHHHCCC	18.45	28857561
465	Phosphorylation	VDVNTRDTDGFSPLL CCCCCCCCCCCCHHH	34.43	23403867
469	Phosphorylation	TRDTDGFSPLLLAVR CCCCCCCCHHHHHHC	21.84	23403867

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LPP60_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LPP60_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LPP60_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SGK1_HUMAN	SGK1	physical	21063096

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.