| UniProt ID | LONF2_HUMAN | |
|---|---|---|
| UniProt AC | Q1L5Z9 | |
| Protein Name | LON peptidase N-terminal domain and RING finger protein 2 | |
| Gene Name | LONRF2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 754 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MSPEPVPPPPPPQCPGCDRAEPIAQRLEEGDEAFRAGDYEMAAELFRSMLAGLAQPDRGLCLRLGDALARAGRLPEALGAFRGAARLGALRPEELEELAGGLVRAVGLRDRPLSAENPGGEPEAPGEGGPAPEPRAPRDLLGCPRCRRLLHKPVTLPCGLTVCKRCVEPGPARPQVRRVNVVLSGLLEKCFPAECRLRRLAGQARSLQRQQQPEAALLRCDQALELAPDDNSLLLLRAELYLTMKNYEQALQDASAACQNEPLLIKGHQVKAQALSGLGRSKEVLKEFLYCLALNPECNSVKKEAQKVMCEVLFSATANVHENLTSSIQSRLKAQGHSHMNAQALLEEGDAGSSENSSEKSDMLGNTNSSVLYFILGLHFEEDKKALESILPTAPSAGLKRQFPDDVEDAPDLNAPGKIPKKDLSLQRSPNSETEESQGLSLDVTDFECALCMRLLFEPVTTPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEELIFRYLPDELSDRKRIYDEEMSELSNLTRDVPIFVCAMAFPTVPCPLHVFEPRYRLMIRRCMETGTKRFGMCLSAEHAGLSEYGCMLEIKDVRTFPDGSSVVDAIGISRFRVLSHRHRDGYNTADIEYLEDEKVEGPEYEELAALHDSVHQQSVSWFASLQDRMKEQILSHFGVMPDREPEPQSNPSGPAWSWWILAVLPLERKAQLAILGMTSLKERLLAIRRILVIITRKMNSRQELANARERNN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSPEPVPPP ------CCCCCCCCC | 37.66 | 24719451 | |
| 152 | Acetylation | RCRRLLHKPVTLPCG HHHHHHCCCCCCCCC | 40.95 | 19811727 | |
| 164 | Acetylation | PCGLTVCKRCVEPGP CCCCEEHHHHCCCCC | 44.49 | 19811733 | |
| 246 (in isoform 2) | Ubiquitination | - | 34.45 | 21890473 | |
| 246 | Ubiquitination | ELYLTMKNYEQALQD HHHHHHCCHHHHHHH | 34.45 | 21890473 | |
| 290 | Phosphorylation | EVLKEFLYCLALNPE HHHHHHHHHHHHCCC | 7.25 | 24719451 | |
| 300 | Phosphorylation | ALNPECNSVKKEAQK HHCCCHHHHHHHHHH | 47.15 | 24719451 | |
| 361 | Phosphorylation | SENSSEKSDMLGNTN CCCCHHHHHHCCCCH | 24.97 | 22798277 | |
| 373 | Phosphorylation | NTNSSVLYFILGLHF CCHHHHHHHHHHCCC | 6.09 | 22798277 | |
| 400 | Ubiquitination | TAPSAGLKRQFPDDV CCCCCCHHHCCCCCC | 43.14 | - | |
| 425 | Phosphorylation | KIPKKDLSLQRSPNS CCCHHHCCCCCCCCC | 32.37 | 24719451 | |
| 487 | Ubiquitination | APHCPLCKDKLSELL CCCCCCCHHHHHHHH | 66.63 | 22817900 | |
| 489 | Ubiquitination | HCPLCKDKLSELLAS CCCCCHHHHHHHHHC | 39.13 | 22817900 | |
| 489 (in isoform 1) | Ubiquitination | - | 39.13 | 21890473 | |
| 601 | Phosphorylation | LEIKDVRTFPDGSSV EEEEECEECCCCCCH | 39.09 | - | |
| 606 | Phosphorylation | VRTFPDGSSVVDAIG CEECCCCCCHHHHHH | 27.60 | 30242111 | |
| 607 | Phosphorylation | RTFPDGSSVVDAIGI EECCCCCCHHHHHHH | 31.52 | 30242111 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of LONF2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of LONF2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of LONF2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of LONF2_HUMAN !! | ||||
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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