LIIP1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LIIP1_ARATH
• UniProt AC: Q9C5J9
• Protein Name: Small GTPase LIP1 {ECO:0000303|PubMed:17683937}
• Gene Name: LIP1 {ECO:0000303|PubMed:17683937}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 342
• Subcellular Localization: Nucleus . Cytoplasm . The localization is not affected by light, but the nuclear localization is essential for the circadian function.
• Protein Description: Functional small GTPase that acts as a negative factor controlling the light-dependent period shortening of circadian rhythms and light-induced phase resetting during the subjective night. [PubMed: 17683937 May protect the clock from excessive or mistimed light]
• Protein Sequence: MKFWRERERENKEQILAPLCGQVRVLVVGDSGVGKTSLVHLINKGSSIVRPPQTIGCTVGVKHITYGSPASSSSSIQGDSERDFFVELWDVSGHERYKDCRSLFYSQINGVIFVHDLSQRRTKTSLQKWASEVAATGTFSAPLPSGGPGGLPVPYIVVGNKADIAAKEGTKGSSGNLVDAARHWVEKQGLLPSSSEDLPLFESFPGNGGLIAAAKETRYDKEALNKFFRMLIRRRYFSDELPAASPWSISPVPTSSSQRLDEITSDDDQFYKRTSFHGDPYKYNNTIPPLPAQRNLTPPPTLYPQQPVSTPDNYTIPRYSLSSVQETTNNGSARSKRMDINV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
65	Phosphorylation	TVGVKHITYGSPASS EEECEEEECCCCCCC		29654922
66	Phosphorylation	VGVKHITYGSPASSS EECEEEECCCCCCCC		25561503
68	Phosphorylation	VKHITYGSPASSSSS CEEEECCCCCCCCCC		30291188
71	Phosphorylation	ITYGSPASSSSSIQG EECCCCCCCCCCCCC		24243849
72	Phosphorylation	TYGSPASSSSSIQGD ECCCCCCCCCCCCCC		29654922
73	Phosphorylation	YGSPASSSSSIQGDS CCCCCCCCCCCCCCC		19880383
74	Phosphorylation	GSPASSSSSIQGDSE CCCCCCCCCCCCCCC		25561503
75	Phosphorylation	SPASSSSSIQGDSER CCCCCCCCCCCCCCC		29654922
170	Phosphorylation	DIAAKEGTKGSSGNL HHHHHCCCCCCCCCH		23776212
173	Phosphorylation	AKEGTKGSSGNLVDA HHCCCCCCCCCHHHH		30291188
174	Phosphorylation	KEGTKGSSGNLVDAA HCCCCCCCCCHHHHH		23776212
193	Phosphorylation	EKQGLLPSSSEDLPL HHCCCCCCCCCCCCC		27531888
264	Phosphorylation	SQRLDEITSDDDQFY CCCHHCCCCCCCHHH		23776212
265	Phosphorylation	QRLDEITSDDDQFYK CCHHCCCCCCCHHHH		30291188
271	Phosphorylation	TSDDDQFYKRTSFHG CCCCCHHHHHHCCCC		23776212
274	Phosphorylation	DDQFYKRTSFHGDPY CCHHHHHHCCCCCCC		25561503
275	Phosphorylation	DQFYKRTSFHGDPYK CHHHHHHCCCCCCCC		25561503
319	Phosphorylation	DNYTIPRYSLSSVQE CCCEECCCCCCCCEE		25561503
320	Phosphorylation	NYTIPRYSLSSVQET CCEECCCCCCCCEEC		25561503
322	Phosphorylation	TIPRYSLSSVQETTN EECCCCCCCCEECCC		25561503
327	Phosphorylation	SLSSVQETTNNGSAR CCCCCEECCCCCCCC		25561503
328	Phosphorylation	LSSVQETTNNGSARS CCCCEECCCCCCCCC		25561503
332	Phosphorylation	QETTNNGSARSKRMD EECCCCCCCCCCCCC		25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LIIP1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LIIP1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LIIP1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.