LHX5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LHX5_MOUSE
• UniProt AC: P61375
• Protein Name: LIM/homeobox protein Lhx5
• Gene Name: Lhx5
• Organism: Mus musculus (Mouse).
• Sequence Length: 402
• Subcellular Localization: Nucleus .
• Protein Description: Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system..
• Protein Sequence: MMVHCAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKCAGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSSLKEGSLNSVSSCTDRSLSPDLQDPLQDDPKETDNSTSSDKETANNENEEQNSGTKRRGPRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRMKQLSALGARRHAFFRSPRRMRPLGGRLDESEMLGSTPYTYYGDYQSDYYAPGGNYDFFAHGPPSQAQSPADSSFLAASGPGSTPLGALEPPLAGPHGADNPRFTDMISHPDTPSPEPGLPGALHPMPGEVFSGGPSPPFPMSGTSGYSGPLSHPNPELNEAAVW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
140	Phosphorylation	VSSCTDRSLSPDLQD HHHCCCCCCCCCCCC	35.69	28066266
142	Phosphorylation	SCTDRSLSPDLQDPL HCCCCCCCCCCCCCC	20.02	28066266
188	Acetylation	RGPRTTIKAKQLETL CCCCCCEEHHHHHHH	47.65	2415207
190	Acetylation	PRTTIKAKQLETLKA CCCCEEHHHHHHHHH	50.87	2415215
239	Acetylation	RSKERRMKQLSALGA CCHHHHHHHHHHHHH	46.40	6569539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LHX5_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LHX5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LHX5_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of LHX5_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.